dc.creator | Fontalba-Romero, M. I. | es |
dc.creator | López Enriquez, Soledad | es |
dc.creator | Lago-Sampedro, A. | es |
dc.creator | García-Escobar, E. | es |
dc.creator | Pastori, R. L. | es |
dc.creator | Domínguez-Bendala, J. | es |
dc.creator | García-Serrano, S. | es |
dc.date.accessioned | 2022-11-16T16:29:12Z | |
dc.date.available | 2022-11-16T16:29:12Z | |
dc.date.issued | 2021-01-29 | |
dc.identifier.citation | Fontalba-Romero, M.I., López Enriquez, S., Lago-Sampedro, A., García-Escobar, E., Pastori, R.L., Domínguez-Bendala, J. y García-Serrano, S. (2021). Association between the Mediterranean diet and metabolic syndrome with serum levels of miRNA in morbid obesity. Nutrients, 13 (2), 436. https://doi.org/10.3390/nu13020436. | |
dc.identifier.issn | 2072-6643 | es |
dc.identifier.uri | https://hdl.handle.net/11441/139523 | |
dc.description.abstract | Background: The Mediterranean diet (MD) could be involved in the regulation of different
miRNAs related to metabolic syndrome (MS). Methods: We analyzed the serum level of mir-let7a-5p,
mir-21, mir-590, mir-107 and mir-192 in patients with morbid obesity and its association with the MD
and MS. Results: There is an association between the adherence to MD and higher serum levels of
mir-590. Mir-590 was lower in those patients who consumed >2 commercial pastries/week. Mir-let7a
was lower in those who consumed ≥1 sweetened drinks, in those who consumed ≥3 pieces of
fruit/day and in those who consumed less red than white meat. A lower mir-590 and mir-let7a, and a
higher mir-192 level, were found in patients who met the high-density lipoprotein cholesterol (HDL)
criterion of MS. A higher mir-192 was found in those patients who met the triglyceride criterion
of MS and in those with type 2 diabetes (T2DM). Conclusions: There is an association between
specific serum levels of miRNAs and the amount and kind of food intake related to MD. Mir-590 was
positively associated with a healthy metabolic profile and type of diet, while mir-192 was positively
associated with a worse metabolic profile. These associations could be suggestive of a possible
modulation of these miRNAs by food. | es |
dc.format | application/pdf | es |
dc.format.extent | 12 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Nutrients, 13 (2), 436. | |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Mediterranean diet | es |
dc.subject | Metabolic syndrome | es |
dc.subject | miRNA | es |
dc.subject | Morbid obesity | es |
dc.subject | Type 2 diabetes mellitus | es |
dc.title | Association between the Mediterranean diet and metabolic syndrome with serum levels of miRNA in morbid obesity | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Bioquímica Médica y Biología Molecular e Inmunología | es |
dc.relation.projectID | PI-0337-2016 | es |
dc.relation.projectID | PI18/01165 | es |
dc.relation.publisherversion | https://www.mdpi.com/2072-6643/13/2/436 | es |
dc.identifier.doi | 10.3390/nu13020436 | es |
dc.journaltitle | Nutrients | es |
dc.publication.volumen | 13 | es |
dc.publication.issue | 2 | es |
dc.publication.initialPage | 436 | es |
dc.contributor.funder | Consejeria de Salud de la Junta de Andalucia (Spain) | es |
dc.contributor.funder | Instituto de Salud Carlos III (España) | es |