dc.creator | Nepomuceno Chamorro, Juan Antonio | es |
dc.creator | Troncoso Lora, Alicia | es |
dc.creator | Aguilar Ruiz, Jesús Salvador | es |
dc.date.accessioned | 2022-05-27T09:12:17Z | |
dc.date.available | 2022-05-27T09:12:17Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Nepomuceno Chamorro, J.A., Troncoso Lora, A. y Aguilar Ruiz, J.S. (2015). Scatter search-based identification of local patterns with positive and negative correlations in gene expression data. Applied Soft Computing, 35 (October 2015), 637-651. | |
dc.identifier.issn | 1568-4946 | es |
dc.identifier.uri | https://hdl.handle.net/11441/133797 | |
dc.description.abstract | This paper presents a scatter search approach based on linear correlations among genes to find biclusters,
which include both shifting and scaling patterns and negatively correlated patterns contrarily to most of
correlation-based algorithms published in the literature. The methodology established here for compari son is based on a priori biological information stored in the well-known repository Gene Ontology (GO). In
particular, the three existing categories in GO, Biological Process, Cellular Components and Molecular Func tion, have been used. The performance ofthe proposed algorithm has been compared to other benchmark
biclustering algorithms, specifically a group of classical biclustering algorithms and two algorithms that
use correlation-based merit functions. The proposed algorithm outperforms the benchmark algorithms
and finds patterns based on negative correlations. Although these patterns contain important relation ship among genes, they are not found by most of biclustering algorithms. The experimental study also
shows the importance of the size in a bicluster in addition to the value of its correlation. In particular, the
size of a bicluster has an influence over its enrichment in a GO term | es |
dc.description.sponsorship | Ministerio de Ciencia e Innovación TIN2011-28956-C02-00 | es |
dc.description.sponsorship | Junta de Andalucía P12-TIC-1728 | es |
dc.description.sponsorship | Universidad Pablo de Olavide APPB813097 | es |
dc.format | application/pdf | es |
dc.format.extent | 15 | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.relation.ispartof | Applied Soft Computing, 35 (October 2015), 637-651. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Biclustering | es |
dc.subject | Scatter Search | es |
dc.subject | Gene Expression Data | es |
dc.title | Scatter search-based identification of local patterns with positive and negative correlations in gene expression data | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Lenguajes y Sistemas Informáticos | es |
dc.relation.projectID | TIN2011-28956-C02-00 | es |
dc.relation.projectID | P12-TIC-1728 | es |
dc.relation.projectID | APPB813097 | es |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S1568494615003683?via%3Dihub | es |
dc.identifier.doi | 10.1016/j.asoc.2015.06.019 | es |
dc.journaltitle | Applied Soft Computing | es |
dc.publication.volumen | 35 | es |
dc.publication.issue | October 2015 | es |
dc.publication.initialPage | 637 | es |
dc.publication.endPage | 651 | es |
dc.identifier.sisius | 20847777 | es |
dc.contributor.funder | Ministerio de Ciencia e Innovación (MICIN). España | es |
dc.contributor.funder | Junta de Andalucía | es |
dc.contributor.funder | Universidad Pablo de Olavide | es |