dc.creator | Gómez Gálvez, Pedro | es |
dc.creator | Anbari, Samira | es |
dc.creator | Escudero Cuadrado, Luis María | es |
dc.creator | Buceta, Javier | es |
dc.date.accessioned | 2022-03-14T11:57:09Z | |
dc.date.available | 2022-03-14T11:57:09Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Gómez Gálvez, P., Anbari, S., Escudero Cuadrado, L.M. y Buceta, J. (2021). Mechanics and self-organization in tissue development. Seminars in Cell and Developmental Biology, 120, 147-159. | |
dc.identifier.issn | 1084-9521 | es |
dc.identifier.issn | 1096-3634 | es |
dc.identifier.uri | https://hdl.handle.net/11441/130753 | |
dc.description.abstract | Self-organization is an all-important feature of living systems that provides the means to achieve specialization and functionality at distinct spatio-temporal scales. Herein, we review this concept by addressing the packing organization of cells, the sorting/compartmentalization phenomenon of cell populations, and the propagation of organizing cues at the tissue level through traveling waves. We elaborate on how different theoretical models and tools from Topology, Physics, and Dynamical Systems have improved the understanding of self-organization by shedding light on the role played by mechanics as a driver of morphogenesis. Altogether, by providing a historical perspective, we show how ideas and hypotheses in the field have been revisited, developed, and/or rejected and what are the open questions that need to be tackled by future research. | es |
dc.description.sponsorship | Ministerio de Economía, Industria y Competitividad de España y Fondos FEDER de la Unión Euopea. BFU2016-74975-P | es |
dc.description.sponsorship | Ministerio de Ciencia e Innovación de España. PID2019-103900GB-I00 | es |
dc.format | application/pdf | es |
dc.format.extent | 13 p. | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.relation.ispartof | Seminars in Cell and Developmental Biology, 120, 147-159. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Self-organization | es |
dc.subject | Cell packing | es |
dc.subject | Cell sorting | es |
dc.subject | Traveling waves | es |
dc.subject | Epithelia | es |
dc.subject | ERK | es |
dc.subject | Developmental mechanics | es |
dc.subject | Developmental mechanisms | es |
dc.title | Mechanics and self-organization in tissue development | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Biología Celular | es |
dc.relation.projectID | BFU2016-74975-P | es |
dc.relation.projectID | PID2019-103900GB-I00 | es |
dc.relation.publisherversion | https://doi.org/10.1016/j.semcdb.2021.07.003 | es |
dc.identifier.doi | 10.1016/j.semcdb.2021.07.003 | es |
dc.journaltitle | Seminars in Cell and Developmental Biology | es |
dc.publication.volumen | 120 | es |
dc.publication.initialPage | 147 | es |
dc.publication.endPage | 159 | es |
dc.contributor.funder | Ministerio de Economía y Competitividad (MINECO). España | es |
dc.contributor.funder | European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER) | es |
dc.contributor.funder | Ministerio de Ciencia e Innovación (MICIN). España | es |