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Biocompatibility Study of a Commercial Printed Circuit Board for Biomedical Applications: Lab-on-PCB for Organotypic Retina Cultures

dc.creatorUrbano Gámez, Jesús Davides
dc.creatorValdés Sánchez, Lourdeses
dc.creatorAracil Fernández, Carmenes
dc.creatorDe la Cerda, Bertaes
dc.creatorPerdigones Sánchez, Franciscoes
dc.creatorPlaza Reyes, Álvaroes
dc.creatorDíaz Corrales, Francisco Javieres
dc.creatorRelimpio López, Isabeles
dc.creatorQuero Reboul, José Manueles
dc.date.accessioned2022-02-09T14:46:56Z
dc.date.available2022-02-09T14:46:56Z
dc.date.issued2021-11
dc.identifier.citationUrbano Gámez, J.D., Valdés Sánchez, L., Aracil Fernández, C., De la Cerda, B., Perdigones Sánchez, F., Plaza Reyes, Á.,...,Quero Reboul, J.M. (2021). Biocompatibility Study of a Commercial Printed Circuit Board for Biomedical Applications: Lab-on-PCB for Organotypic Retina Cultures. Micromachines, 12 (12). Article number 1469.
dc.identifier.issnEISSN 2072-666Xes
dc.identifier.urihttps://hdl.handle.net/11441/129808
dc.description.abstractPrinted circuit board (PCB) technology is well known, reliable, and low-cost, and its application to biomedicine, which implies the integration of microfluidics and electronics, has led to Lab-on-PCB. However, the biocompatibility of the involved materials has to be examined if they are in contact with biological elements. In this paper, the solder mask (PSR-2000 CD02G/CA-25 CD01, Taiyo Ink (Suzhou) Co., Ltd., Suzhou, China) of a commercial PCB has been studied for retinal cultures. For this purpose, retinal explants have been cultured over this substrate, both on open and closed systems, with successful results. Cell viability data shows that the solder mask has no cytotoxic effect on the culture allowing the application of PCB as the substrate of customized microelectrode arrays (MEAs). Finally, a comparative study of the biocompatibility of the 3D printer Uniz zSG amber resin has also been carried out.es
dc.description.sponsorshipUnión Europea US-1265983es
dc.description.sponsorshipConsejería de Economía, Conocimiento, Empresas y Universidad de la Junta de Andalucía US-1265983es
dc.formatapplication/pdfes
dc.format.extent12 p.es
dc.language.isoenges
dc.publisherMDPIes
dc.relation.ispartofMicromachines, 12 (12). Article number 1469.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectLab-on-PCBes
dc.subjectPrinted circuit boardes
dc.subjectOrganotypic culturees
dc.subjectBiomedical applicationses
dc.titleBiocompatibility Study of a Commercial Printed Circuit Board for Biomedical Applications: Lab-on-PCB for Organotypic Retina Cultureses
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Ingeniería Electrónicaes
dc.relation.projectIDUS-1265983es
dc.relation.publisherversionhttps://doi.org/10.3390/mi12121469es
dc.identifier.doi10.3390/mi12121469es
dc.contributor.groupUniversidad de Sevilla. TIC109: Tecnología Electrónicaes
dc.journaltitleMicromachineses
dc.publication.volumen12es
dc.publication.issue12es
dc.publication.initialPageArticle number 1469es
dc.contributor.funderEuropean Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER)es
dc.contributor.funderJunta de Andalucíaes

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