Por motivos de mantenimiento se ha deshabilitado el inicio de sesión temporalmente. Rogamos disculpen las molestias.

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dc.creatorDubuisson, Nicolases
dc.creatorVersele, Romaines
dc.creatorDavis López de Carrizosa, María Américaes
dc.creatorSelvais, Camille M.es
dc.creatorBrichard, Sonia M.es
dc.creatorAbou-Samra, Micheles
dc.date.accessioned2021-12-01T16:58:56Z
dc.date.available2021-12-01T16:58:56Z
dc.date.issued2021
dc.identifier.citationDubuisson, N., Versele, R., Davis López de Carrizosa, M.A., Selvais, C.M., Brichard, S.M. y Abou-Samra, M. (2021). Walking down skeletal muscle lane: from inflammasome to disease. Cells, 10 (11), 3023.
dc.identifier.issn2073-4409es
dc.identifier.urihttps://hdl.handle.net/11441/127916
dc.description.abstractOver the last decade, innate immune system receptors and sensors called inflammasomes have been identified to play key pathological roles in the development and progression of numerous diseases. Among them, the nucleotide-binding oligomerization domain (NOD-), leucine-rich repeat (LRR-) and pyrin domain-containing protein 3 (NLRP3) inflammasome is probably the best characterized. To date, NLRP3 has been extensively studied in the heart, where its effects and actions have been broadly documented in numerous cardiovascular diseases. However, little is still known about NLRP3 implications in muscle disorders affecting non-cardiac muscles. In this review, we summarize and present the current knowledge regarding the function of NLRP3 in diseased skeletal muscle, and discuss the potential therapeutic options targeting the NLRP3 inflammasome in muscle disorders.es
dc.description.sponsorshipFrench Association against Myopathies H121203009es
dc.description.sponsorshipFund for Scientific Research-FNRS PDR/T.0026.21es
dc.formatapplication/pdfes
dc.format.extent26 p.es
dc.language.isoenges
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)es
dc.relation.ispartofCells, 10 (11), 3023.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectCritical limb ischemiaes
dc.subjectInflammasomees
dc.subjectMetabolic syndromees
dc.subjectMmyotrophic lateral sclerosises
dc.subjectMyopathieses
dc.subjectNLRP3es
dc.subjectPyroptosises
dc.subjectSepsises
dc.subjectSkeletal musclees
dc.titleWalking down skeletal muscle lane: from inflammasome to diseasees
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Fisiologíaes
dc.relation.projectIDH121203009es
dc.relation.projectIDPDR/T.0026.21es
dc.relation.publisherversionhttps://doi.org/10.3390/cells10113023es
dc.identifier.doi10.3390/cells10113023es
dc.journaltitleCellses
dc.publication.volumen10es
dc.publication.issue11es
dc.publication.initialPage3023es

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