Artículo
Effect of a ketogenic diet on the nutritional parameters of obese patients: A systematic review and meta-analysis
Autor/es | López Espinoza, Miguel Ángel
Chacón Moscoso, Salvador ![]() ![]() ![]() ![]() ![]() ![]() ![]() Sanduvete Chaves, Susana ![]() ![]() ![]() ![]() ![]() ![]() ![]() Ortega Maureira, María José Barrientos Bravo, Tamara |
Departamento | Universidad de Sevilla. Departamento de Psicología Experimental |
Fecha de publicación | 2021 |
Fecha de depósito | 2021-08-27 |
Publicado en |
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Resumen | The effect of a ketogenic diet (KD) on biochemical parameters and nutritional status has been the subject of debate over the years, as several randomized clinical trials (RCTs) obtained different results. Method: A systematic ... The effect of a ketogenic diet (KD) on biochemical parameters and nutritional status has been the subject of debate over the years, as several randomized clinical trials (RCTs) obtained different results. Method: A systematic review and random-effects meta-analysis of RCTs comparing KD with a balanced diet was performed by means of a search of PubMed, Cochrane Library, Scopus, and Web of Science. Trials where the method for measuring the response variables was unclear, those that considered pathologies other than chronic non-communicable diseases and those with participants receiving pharmacological treatment for obesity were excluded from the comparison. Results: Of the studies included in the meta-analysis, no statistically significant standardized mean differences were observed for body mass index (BMI) (d = −0.457, p = 0.359), total cholesterol, COL-T (d = 0.230, p = 0.591), high-density lipoprotein, HDL (d = −0.028, p = 0.934), low-density lipoprotein, LDL (d = 0.528, p = 0.173), or triglycerides, TG (d = −0.283, p = 0.222), with high values of heterogeneity. The percentage of women included in the studies is a significant moderating variable in terms of BMI ratio (z = −6.68, p < 0.001) and TG (z = −2.27, p = 0.023). Conclusion: A KD shows no more benefits on nutritional parameters than a balanced diet, and adverse effects of being on the diet are sometimes reported. |
Agencias financiadoras | Fondo Nacional de Desarrollo Científico y Tecnológico (FONDECYT). Chile Junta de Andalucía |
Identificador del proyecto | 1190945
![]() US-1263096 ![]() |
Cita | López Espinoza, M.Á., Chacón Moscoso, S., Sanduvete Chaves, S., Ortega Maureira, M.J. y Barrientos Bravo, T. (2021). Effect of a ketogenic diet on the nutritional parameters of obese patients: A systematic review and meta-analysis. Nutrients, 13 (9), Article 2946. |
Ficheros | Tamaño | Formato | Ver | Descripción |
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nutrients-13-02946-v2.pdf | 2.986Mb | ![]() | Ver/ | |
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