dc.creator | Hernández-Suarez, Argimiro | es |
dc.creator | Rizo-Gorrita, María | es |
dc.creator | Suárez-Vega, Dubraska | es |
dc.creator | Velazco, Gladys | es |
dc.creator | Rodríguez Gelfenstein, Iván | es |
dc.creator | Serrera Figallo, María de los Ángeles | es |
dc.creator | Torres-Lagares, Daniel | es |
dc.date.accessioned | 2021-07-14T11:00:59Z | |
dc.date.available | 2021-07-14T11:00:59Z | |
dc.date.issued | 2021-04-29 | |
dc.identifier.citation | Hernández-Suarez, A., Rizo-Gorrita, M., Suárez-Vega, D., Velazco, G., Rodríguez Gelfenstein, I., Serrera Figallo, M.d.l.Á. y Torres-Lagares, D. (2021). Effectiveness of silicon platelet-rich fibrin and autologous bone on bone regeneration in rabbit calvarian defects: a radiological and histological study. Applied sciences-basel, 11 (9) | |
dc.identifier.issn | 2076-3417 | es |
dc.identifier.uri | https://hdl.handle.net/11441/116126 | |
dc.description.abstract | Repairing bone defects in oral surgery often requires the use of bone regeneration techniques. Silicon is an element that has been employed as regeneration material in several studies. In
our study, silicon was combined with autologous bone and platelet-rich fibrin (PRF) membranes
to analyse the behaviour of this element in bone regeneration. Four circumferential defects were
created in the cranial vault of five New Zealand rabbits. The following elements were applied to
the regeneration of the defects: (P): PRF; (S): silicon and (B): autologous bone, with the following
distribution of study groups: Group 1 (PSB); Group 2 (PS); Group 3 (SB) and Group 4 (CONTROL):
unregenerate group. The animals were sacrificed after 3 weeks. Computed microtomography studies
(µ-CT) were carried out, as well as histomorphometric ones. The ANOVA statistical test was used
with a Bonferroni post-hoc test to compare the results (p ≤ 0.05). Radiologically, groups PSB and
SB were better as far as quantity and percentage of healthy bone observed, but not significantly
compared to the control group. The PS group was significantly worse. The histological test revealed
that the PSB group was the one to present the largest area, percentage and perimeter of mineralised
bone. On evaluating the forming bone (osteoid), no difference was observed across the groups with
the exception of the bone perimeter, where the SB group was significantly better. The bone height
variable showed no significant differences. In conclusion we can state that the combination of PRF,
autologous bone and silicon provides good results at 3 weeks whilst the PS group shows the worst
results. This highlights the importance of autologous bone forming part of the graft material in order
for the bone to mineralise. | es |
dc.format | application/pdf | es |
dc.format.extent | 13 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Applied sciences-basel, 11 (9) | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Bone regeneration | es |
dc.subject | Silicon | es |
dc.subject | Platelet-rich fibrin | es |
dc.subject | PRF | es |
dc.subject | Autologous bone | es |
dc.title | Effectiveness of silicon platelet-rich fibrin and autologous bone on bone regeneration in rabbit calvarian defects: a radiological and histological study | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Estomatología | es |
dc.relation.publisherversion | https://www.mdpi.com/journal/applsci | es |
dc.identifier.doi | 10.3390/app11094074 | es |
dc.journaltitle | Applied sciences-basel | es |
dc.publication.volumen | 11 | es |
dc.publication.issue | 9 | es |