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dc.creatorSarrias Arrabal, Estebanes
dc.creatorEichau Madueño, Saraes
dc.creatorGalvao Carmona, Alejandroes
dc.creatorDomínguez Vázquez, Evaes
dc.creatorIzquierdo Ayuso, Guillermoes
dc.creatorVázquez Marrufo, Manueles
dc.date.accessioned2021-06-22T12:22:40Z
dc.date.available2021-06-22T12:22:40Z
dc.date.issued2021
dc.identifier.citationSarrias Arrabal, E., Eichau Madueño, S., Galvao Carmona, A., Domínguez Vázquez, E., Izquierdo Ayuso, G. y Vázquez Marrufo, M. (2021). Deficits in Early Sensory and Cognitive Processing Are Related to Phase and Nonphase EEG Activity in Multiple Sclerosis Patients. Brain Sciences, 11 (5), Article 629.
dc.identifier.issn2076-3425es
dc.identifier.urihttps://hdl.handle.net/11441/114719
dc.description.abstractCurrently, there is scarce knowledge about the relation between spectral bands modulations and the basis of cognitive impairment in multiple sclerosis (MS). In this sense, analyzing the evoked or phase activity can confirm results from traditional event-related potential (ERP) studies. However, studying the induced or nonphase activity may be necessary to elucidate hidden compensatory or affected cognitive mechanisms. In this study, 30 remitting-relapsing multiple sclerosis patients and 30 healthy controls (HCs) matched in sociodemographic variables performed a visual oddball task. The main goal was to analyze phase and nonphase alpha and gamma bands by applying temporal spectral evolution (TSE) and its potential relation with cognitive impairment in these patients. The behavioural results showed slower reaction time and poorer accuracy in MS patients compared to controls. In contrast, the time-frequency analysis of electroencephalography (EEG) revealed a delay in latency and lower amplitude in MS patients in evoked and induced alpha compared to controls. With respect to the gamma band, there were no differences between the groups. In summary, MS patients showed deficits in early sensorial (evoked alpha activity) and cognitive processing (induced alpha activity in longer latencies), whereas the induced gamma band supported the hypothesis of its role in translation of attentional focus (induced activity) and did not show strong activity in this paradigm (visual oddball).es
dc.description.sponsorshipMinisterio de Economía y Competitividad de España PSI2016- 78133-Pes
dc.formatapplication/pdfes
dc.format.extent13 p.es
dc.language.isoenges
dc.publisherMDPIes
dc.relation.ispartofBrain Sciences, 11 (5), Article 629.
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectAlphaes
dc.subjectOddballes
dc.subjectEEGes
dc.subjectGammaes
dc.subjectMultiple sclerosises
dc.subjectEvokedes
dc.subjectInducedes
dc.titleDeficits in Early Sensory and Cognitive Processing Are Related to Phase and Nonphase EEG Activity in Multiple Sclerosis Patientses
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Psicología Experimentales
dc.relation.projectIDPSI 2016- 78133-Pes
dc.identifier.doi10.3390/brainsci11050629es
dc.journaltitleBrain Scienceses
dc.publication.volumen11es
dc.publication.issue5es
dc.publication.initialPageArticle 629es
dc.contributor.funderMinisterio de Economía y Competitividad (MINECO). Españaes

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