Artículo
Modular Assembly of Cell Systems Biology Models Using P Systems
Autor/es | Romero Campero, Francisco José
Twycross, Jamie Bennett, Malcolm Cámara, Miguel Krasnogor, Natalio |
Departamento | Universidad de Sevilla. Departamento de Ciencias de la Computación e Inteligencia Artificial |
Fecha de publicación | 2009 |
Fecha de depósito | 2021-05-31 |
Publicado en |
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Resumen | In this paper we propose an extension of the modelling framework based on P systems
which explicitly includes modularity. Modularisation in cellular systems can be produced by chemical
specificity and spatial localisation ... In this paper we propose an extension of the modelling framework based on P systems which explicitly includes modularity. Modularisation in cellular systems can be produced by chemical specificity and spatial localisation in different compartments. Both these features can be easily specified and analysed in P systems using sets of rewriting rules to describe chemical specificity and membranes to represent spatial localisation. Our methodology enables the assembly of cell systems biology models by combining modules which represents functional subsystems. A case study consisting of a bacterial colony system is presented to illustrate our approach. |
Cita | Romero Campero, F.J., Twycross, J., Bennett, M., Cámara, M. y Krasnogor, N. (2009). Modular Assembly of Cell Systems Biology Models Using P Systems. International Journal of Foundations of Computer Science, 20 (3), 427-442. |
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