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Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin
(Company of Biologists Limited, 2018-06-21)
Cisplatin and derivatives are commonly used as chemotherapeutic agents. Although the cytotoxic action of cisplatin on cancer cells is very efficient, clinical oncologists need to deal with two major difficulties, namely ...
Artículo
Intracellular Trafficking and Persistence of Acinetobacter baumannii Requires Transcription Factor EB
(American Society for Microbiology, 2018-03-28)
Acinetobacter baumannii is a significant human pathogen associated with hospital-acquired infections. While adhesion, an initial and important step in A. baumannii infection, is well characterized, the intracellular ...
Artículo
Redox-dependent and redox-independent functions of Caenorhabditis elegans thioredoxin 1
(Elsevier, 2019-06)
Thioredoxins (TRX) are traditionally considered as enzymes catalyzing redox reactions. However, redox-independent functions of thioredoxins have been described in different organisms, although the underlying molecular ...