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Listar Instituto de Biomedicina de Sevilla (IBIS) por autor "Álava Casado, Enrique de"
Mostrando ítems 1-7 de 7
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Artículo
Breakthrough Technologies Reshape the Ewing Sarcoma Molecular Landscape
Salguero-Aranda, Carmen; Amaral, Ana Teresa; Olmedo Pelayo, Joaquín; Diaz-Martin, Juan; Álava Casado, Enrique de (MDPI, 2020)Ewing sarcoma is a highly aggressive round cell mesenchymal neoplasm, most often occurring in children and young adults. ...
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Artículo
HMGA2 overexpression predicts relapse susceptibility of blastemal Wilms tumor patients
Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; García Mejías, Rosa; Ramírez Villar, Gema; Sáez, Carmen; Álava Casado, Enrique de (Impact Journals, 2017)Wilms tumor (WT) is an embryonal malignant neoplasm of the kidney that accounts for 6–7% of all childhood cancers. WT ...
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Artículo
Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients
Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; Pascual Vaca, Diego; García Mejías, Rosa; Marcilla, David; Ramírez Villar, Gema; Álava Casado, Enrique de (Impact Journals, 2017)Wilms tumour (WT) is the most common renal tumour in children. Most WT patients respond to chemotherapy, but subsets of ...
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Artículo
Phosphorylated-insulin growth factor I receptor (p-IGF1R) and metalloproteinase-3 (MMP3) expression in advanced gastrointestinal stromal tumors (GIST). A GEIS 19 study
Maurel, Joan; López-Pousa, Antonio; Calabuig, Silvia; Bagué, Silvia; García del Muro, Xavier; Sanjuan, Xavier; Álava Casado, Enrique de (BMC, 2016-06-29)Background: Most GISTs have mutations in KIT or PDGFRA. Patients with advanced GIST with KIT exon 9, PDGFRA mutation or ...
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Artículo
RING1B contributes to Ewing sarcoma development by repressing the Na(V)1.6 sodium channel and the NF-kappa B pathway, independently of the fusion oncoprotein
Hernández Muñoz, Inmaculada; Figuerola, Elisabeth; Sánchez Molina, Sara; Rodríguez, Eva; Fernández Mariño, María Isabel; Pardo Pastor, Carlos; Álava Casado, Enrique de; Mora, Jaume (Impact Journals, 2016-06-15)Ewing sarcoma (ES) is an aggressive tumor defined by EWSR1 gene fusions that behave as an oncogene. Here we demonstrate ...
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Artículo
The second European interdisciplinary Ewing sarcoma research summit – A joint effort to deconstructing the multiple layers of a complex disease
Kovar, Heinrich; Amatruda, James; Brunet, Erika; Burdach, Stefan; Cidre-Aranaz, Florencia; Álava Casado, Enrique de (Impact Journals LLC, 2016-01-18)Despite multimodal treatment, long term outcome for patients with Ewing sarcoma is still poor. The second “European ...
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Artículo
VE-Cadherin modulates β-catenin/TCF-4 to enhance vasculogenic mimicry
Delgado-Bellido, Daniel; Zamudio-Martínez, Esteban; Fernández-Cortés, Mónica; Herrera-Campos, Ana Belén; Olmedo Pelayo, Joaquín; Jordán Pérez, Carmen; Álava Casado, Enrique de; Oliver, F. J. (Nature Publishing Group, 2023)Vasculogenic Mimicry (VM) refers to the capacity to form a blood network from aggressive cancer cells in an independent ...