Browsing Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) by Subject "R loop"
Now showing items 1-4 of 4
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Chapter of Book
Detection of DNA-RNA hybrids in vivo
(Humana Press Inc., 2018)DNA-RNA hybrids form naturally during essential cellular functions such as transcription and replication. However, they ...
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Article
Gene gating at nuclear pores prevents the formation of R loops
(Taylor and Francis Ltd., 2018)Transcription is an important source of genetic variability. A large amount of transcription-associated genome variation ...
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Article
The DNA damage response acts as a safeguardagainst harmful DNA–RNA hybrids ofdifferent origins
(EMBO Press, 2019-07-24)Despite playing physiological roles in specific situations, DNA–RNA hybrids threat genome integrity. To investigate how ...
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Article
Yra1-bound RNA–DNA hybrids cause orientation-independent transcription– replication collisions and telomere instability
(Cold Spring Harbor Laboratory Press, 2018)R loops are an important source of genome instability, largely due to their negative impact on replication progression. ...