Browsing Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) by Issue Date
Now showing items 1-20 of 188
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PhD Thesis
Control genético de las deleciones entre secuencias repetidas directas en Saccaromyces cerevisiae
(1996)Los genomios de todos los organismos están constituidos por un número variable de secuencias repetidas, que pueden llegar ...
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PhD Thesis
Elongación transcripcional en Saccharomyces Cerevisiae influencia en el control del ciclo celular y nuevas herramientas para su estudio "in vivo"
(2007)La transcripción es el proceso mediante el cual la información genética, contenida en el DNA, es expresada en forma de ...
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CDK targets Sae2 to control DNA-end resection and homologous recombination
(Nature Publishing Group, 2008)DNA double-strand breaks (DSBs) are repaired by two principal mechanisms: non-homologous end-joining (NHEJ) and homologous ...
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Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition
(Wiley-Blackwell, 2009)Dysfunctions of the ubiquitin proteasome system (UPS) have been proposed to be involved in the aetiology and/or progression ...
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Transcription at the proximity of the nuclear pore: A role for the THP1-SAC3-SUS1-CDC31 (THSC) complex
(Landes Bioscience, 2009)A key aspect of eukaryotic gene expression is the coupling of transcription with RNA processing, polyadenylation and export. ...
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Golgi localisation of GMAP210 requires two distinct cis-membrane binding mechanisms
(BMC, 2009)Background The Golgi apparatus in mammals appears as a ribbon made up of interconnected stacks of flattened cisternae ...
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PhD Thesis
Inestabilidad genética asociada a defectos en el complejo TFIIH
(2010)Los organismos eucarióticos poseen múltiples mecanismos para preservar la integridad de su información genética. Ésta puede ...
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Immunohistochemical assessment of Pax8 expression during pancreatic islet development and in human neuroendocrine tumors
(Springer Verlag, 2011)The paired box transcription factor Pax8 is critical for development of the eye, thyroid gland as well as the urinary and ...
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TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage
(American Society for Biochemistry and Molecular Biology, 2011)Topoisomerase II (Top2) activity involves an intermediate in which the topoisomerase is covalently bound to a DNA double-strand ...
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PS Integrins and Laminins: Key Regulators of Cell Migration during Drosophila Embryogenesis
(Public Library of Science, 2011)During embryonic development, there are numerous cases where organ or tissue formation depends upon the migration of ...
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Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers
(2011)One key step in gene expression is the biogenesis of mRNA ribonucleoparticle complexes (mRNPs). Formation of the mRNP ...
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The Rad50 coiled-coil domain is indispensable for Mre11 complex functions
(Nature Publishing Group, 2011)The Mre11 complex (Mre11, Rad50 and Xrs2 in Saccharomyces cerevisiae) influences diverse functions in the DNA damage ...
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Zim17/Tim15 links mitochondrial iron–sulfur cluster biosynthesis to nuclear genome stability
(Oxford University Press, 2011)Genomic instability is related to a wide-range of human diseases. Here, we show that mitochondrial iron–sulfur cluster ...
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