Listar Artículos (Química Orgánica y Farmacéutica) por fecha de publicación
Mostrando ítems 61-80 de 171
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Artículo
Final results of the telaprevir access program: Fibroscan values predict safety and efficacy in hepatitis c patients with advanced fibrosis or cirrhosis
(Public Library of Science, 2015)Background: Liver stiffness determined by transient elastography is correlated with hepatic fibrosis stage and has high ...
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Artículo
Synthesis of 1D-glyconanomaterials by a hybrid noncovalent–covalent functionalization of single wall carbon nanotubes: a study of their selective interactions with lectins and with live cells
(Royal Society of Chemistry, 2015)To take full advantage of the remarkable applications of carbon nanotubes in different fields, there is a need to develop ...
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Síntesis estereoselectiva de una nueva familia de beta -aminoésteres de interés farmacológico como inhibidores potenciales de la agregación plaquetaria.
(Universidad pablo de Olavide, 2015)Motivación: La utilización de compuestos estereoquímicamente puros presenta numerosas ventajas frente al uso de racematos ...
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Evaluation of the Bioavailability and Metabolism of Nitroderivatives of Hydroxytyrosol Using Caco-2 and HepG2 Human Cell Models
(American Chemical Society, 2016)Considering that nitrocatechols present putative effects against Parkinson's disease, the absorption and metabolism of ...
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Pseudo enantiomeric mixed s/p ligands derived from carbohydrates for the 1,4-addition of phenyl boronic acid to cyclohexenone
(Royal Society of Chemistry, 2016)The application of phosphinite-thioglycosides and phosphine-thioglycosides ligands in the Rh(I)-catalyzed 1,4-addition of ...
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Tyrosol and hydroxytyrosol derivatives as antitrypanosomal and antileishmanial agents
(Elsevier, 2016)Trypanosomiasis and leishmaniasis keep being a real challenge for health and development of African countries. Existing ...
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Cytotoxic, Antiangiogenic and Antitelomerase Activity of Glucosyl- and Acyl- Resveratrol Prodrugs and Resveratrol Sulfate Metabolites
(Wiley-Blackwell, 2016)Resveratrol (RES) is a natural polyphenol with relevant and varied biological activity. However, its low bioavailability ...
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Synthetic Polymers from Sugar-Based Monomers
(American Chemical Society, 2016) -
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Hydroxytyrosol and tyrosol sulfate metabolites protect against the oxidized cholesterol pro-oxidant effect in Caco-2 human enterocyte-like cells
(Royal Society of Chemistry, 2016)The aim of this study was to investigate the ability of the sulfate metabolites of hydroxytyrosol (HT) and tyrosol (TYR) ...
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Ponencia
Design and synthesis of supramolecular hydrogels for biomedical applications
(Universidad Pablo de Olavide, 2016)Motivation: Only a few cells in the human organism keep their ability to regenerate. Hence, modern medical research intends ...
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Glucose–Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA
(Wiley-Blackwell, 2016)Noncovalent forces rule the interactions between biomolecules. Inspired by a biomolecular interaction found in aminoglycoside–RNA ...
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Identifying Coordination Geometries of Metal Aquaions in Water: Application to the Case of Lanthanoid and Actinoid Hydrates
(American Chemical Society, 2016)The angular distribution function (ADF) associated with the oxygen-metal ion-oxygen angle (OMO) of several trivalent ...
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Sulfinamide Phosphinates as Chiral Catalysts for the Enantioselective Organocatalytic Reduction of Imines
(American Chemical Society, 2016-07)A new type of chiral sulfinamide phosphinate catalysts with up to three stereogenic centers, readily accessible from ...
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Multifunctional Magnetic and Upconverting Nanobeads as Dual Modal Imaging Tools
(American Chemical Society, 2017)We report the fabrication of aqueous multimodal imaging nanocomposites based on superparamagnetic nanoparticles (MNPs) and ...
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Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells
(Elsevier, 2017)The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative ...
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Tyrosol and its metabolites as antioxidative and anti-inflammatory molecules in human endothelial cells
(Royal Society of Chemistry, 2017)Tyrosol (Tyr) is a phenolic compound found in virgin olive oil. After ingestion, Tyr undergoes extensive first pass ...
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Highly water-stable rare ternary Ag-Au-Se nanocomposites as long blood circulation time X-ray computed tomography contrast agents
(Royal Society of Chemistry, 2017)X-ray computed tomography (CT) is a powerful and widely used medical non-invasive technique that often requires intravenous ...
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Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification
(Elsevier, 2017)A library of 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyrans has been synthesized as a new family of non-peptide ...
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pH-Responsive Polymeric Nanoparticles as Drug Delivery Systems
(JSciMed Central, 2017-04)Micelles are excellent devices to be used as controlled drug delivery systems since they exhibit the ability to protect ...
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Core cross-linked nanoparticles from self-assembling polyfma-based micelles. Encapsulation of lipophilic molecules
(Elsevier, 2017-04)The present work describes the preparation of stable organic nanoparticles with potential use as “smart” drug delivery ...