Buscar
Mostrando ítems 1-10 de 36
Artículo
Late presentation of chronic HBV and HCV patients seeking first time specialist care in Spain: a 2-year registry review
(Nature Publishing Group, 2021)
Chronic viral hepatitis infection affects an estimated 325 million people globally. People who initiate treatment after significant disease progression face increased risk of severe liver complications and death. Data are ...
Artículo
Assessing the impact of COVID-19 on liver cancer management (CERO-19)
(Elsevier BV, 2021)
Background & Aims: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated whether ...
Artículo
PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis
(ELSEVIER SCIENCE BV, 2021)
Background & Aims: Acute decompensation (AD) of cirrhosis may present without acute-on-chronic liver failure (ACLF) (AD No ACLF), or with ACLF (AD-ACLF), defined by organ failure(s). Herein, we aimed to analyze and ...
Artículo
European 'NAFLD Preparedness Index' - Is Europe ready to meet the challenge of fatty liver disease?
(Elsevier BV, 2021)
Background & Aims: Non-alcoholic fatty liver disease (NAFLD), which is closely associated with obesity, metabolic syndrome, and diabetes, is a highly prevalent emerging condition that can be optimally managed through a ...
Artículo
Combination of squamous cell carcinoma antigen immunocomplex and alpha-fetoprotein in mid- and long-term prediction of hepatocellular carcinoma among cirrhotic patients
(BAISHIDENG PUBLISHING GROUP INC, 2021)
BACKGROUND The combination of alpha-fetoprotein (AFP) and squamous cell carcinoma antigen immunocomplex (SCCA-IgM) have been proposed for its use in the screening of hepatocellular carcinoma (HCC). Current screening ...
Artículo
Impact of COVID-19 on liver disease: From the experimental to the clinic perspective.
(Baishideng Publishing Group Inc, 2021)
Coronavirus disease 2019 (COVID-19) has caused a global pandemic unprecedented in over a century. Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a predominantly respiratory infection, various ...
Artículo
Mistranslation drives alterations in protein levels and the effects of a synonymous variant at the fibroblast growth factor 21 locus
(WILEY, 2021)
Fibroblast growth factor 21 (FGF21) is a liver-derived hormone with pleiotropic beneficial effects on metabolism. Paradoxically, FGF21 levels are elevated in metabolic diseases. Interventions that restore metabolic ...
Artículo
Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis: A longitudinal study of 1893 biopsy-proven nonalcoholic fatty liver disease subjects
(2021-04)
Background and Aim: Histological score systems may not fully capture the essential nonalcoholic steatohepatitis (NASH) features, which is one of the leading causes of screening failure in clinical trials. We assessed the ...
Artículo
acNASH index to diagnose nonalcoholic steatohepatitis: a prospective derivation and global validation study
(EClinicalMedicine, 2021)
Background There is an unmet need for non-invasive biomarkers for the diagnosis of nonalcoholic steatohepatitis (NASH) in non-specialized settings. We aimed to develop and validate a non-invasive test for diagnosing NASH ...
Artículo
COVID-19 and the liver: the chicken or the egg dilema
(Arán Ediciones, S.L., 2021)
After the publication of our meta-analysis, in which we demonstrated that aspartate aminotransferase (AST), alanine aminotransferase (ALT) and total bilirubin were related to a poor prognosis in patients suffering COVID-19, ...