Buscar
Mostrando ítems 1-6 de 6
Artículo
Real-world evidence on non-invasive tests and associated cut-offs used to assess fibrosis in routine clinical practice
(Elsevier, 2022)
Background & Aims Non-invasive tests (NITs) offer a practical solution for advanced fibrosis identification in non-alcoholic fatty liver disease (NAFLD). Despite increasing implementation, their use is not standardised, ...
Artículo
A randomized, controlled trial of the pan-PPAR agonist lanifibranor in NASH
(Massachusetts Medical Society, 2021)
BACKGROUND Management of nonalcoholic steatohepatitis (NASH) is an unmet clinical need. Lanifibranor is a pan-PPAR (peroxisome proliferator–activated receptor) agonist that modulates key metabolic, inflammatory, and ...
Artículo
The European NAFLD Registry: A real-world longitudinal cohort study of nonalcoholic fatty liver disease
(Elsevier, 2020)
Non-Alcoholic Fatty Liver Disease (NAFLD), a progressive liver disease that is closely associated with obesity, type 2 diabetes, hypertension and dyslipidaemia, represents an increasing global public health challenge. There ...
Artículo
A cross-sectional study of the public health response to non-alcoholic fatty liver disease in Europe
(Elsevier, 2020)
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is a growing public health problem worldwide and has become an important field of biomedical inquiry. We aimed to determine whether European countries have mounted ...
Artículo
Cost of non-alcoholic steatohepatitis in Europe and the USA: the GAIN study
(Elsevier BV, 2020)
Background & Aims: Non-alcoholic steatohepatitis (NASH) leads to cirrhosis and is associated with a substantial socioeco- nomic burden, which, coupled with rising prevalence, is a growing public health challenge. However, ...
Artículo
Cirrhosis regression is associated with improved clinical outcomes in patients with nonalcoholic steatohepatitis
(WILEY, 2022)
Background and Aims Surrogate endpoints that predict complications are necessary for assessment and approval of NASH therapies. We assessed associations between histologic and noninvasive tests (NITs) of fibrosis with ...