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Mostrando ítems 1-10 de 21
Artículo
Step-up and step-down treatment approaches for COPD: a holistic view of progressive therapies
(DOVE MEDICAL PRESS LTD, 2021-07-12)
Recent advances in inhaled drugs and a clearer definition of the disease have made the task of managing COPD more complex. Different proposals have been put forward which combine all the available treatments and the ...
Artículo
Characterization of COPD admissions during the first COVID-19 outbreak
(Dove Medical Press LDT, 2021-06-03)
Purpose: Exacerbations of COPD (ECOPD) are a frequent cause of hospitalization that seemed to ameliorate during the COVID outbreak. We aimed to evaluate the clinical characteristics of COPD-related hospital admissions and ...
Artículo
A Comparative Study between Spanish and British SARS-CoV-2 Variants
(MDPI, 2021-11-16)
The study of the interaction between the SARS-CoV-2 spike protein and the angiotensin-converting enzyme 2 (ACE2) receptor is key to understanding binding affinity and stability. In the present report, we sought to investigate ...
Artículo
Dysfunction in the Cystic Fibrosis Transmembrane Regulator in Chronic Obstructive Pulmonary Disease as a Potential Target for Personalised Medicine
(MDPI, 2021-10-10)
In recent years, numerous pathways were explored in the pathogenesis of COPD in the quest for new potential therapeutic targets for more personalised medical care. In this context, the study of the cystic fibrosis transmembrane ...
Artículo
Recomendaciones SEPAR sobre la vacuna COVID-19 en las enfermedades respiratorias
(Elsevier, 2021-04)
La Sociedad Espanola de Neumología y Cirugía Torácica (SEPAR) ha elaborado este documento de reco mendaciones sobre la vacuna para la COVID-19 en las enfermedades respiratorias, con el objetivo de ayudar al personal ...
Artículo
Systematic evaluation of plasma signaling cascades by functional proteomics approaches SARS-CoV-2 infection as model
(Wiley, 2022-09-28)
Purpose Acute phase reactants (APRs) play a critical role in inflammation. The difference in their physiological functions or the different dynamic ranges of these proteins in plasma makes it difficult to detect them ...
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Artículo
Demographic and clinical characteristics of patients with α1-antitrypsin deficiency genotypes PI*ZZ and PI*SZ in the Spanish registry of EARCO
(European Respiratory Society, 2022-09-26)
Background The Spanish registry of α1-antitrypsin deficiency (AATD) integrated in the European Alpha-1 Research Collaboration (EARCO) provides information about the characteristics of patients, in particular those with the ...
Artículo
Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging: a pooled analysis of individual patient data
(European Respiratory Society, 2020)
In 2019, The Global Initiative for Chronic Obstructive Lung Disease (GOLD) modified the grading system for patients with COPD, creating 16 subgroups (1A–4D). As part of the COPD Cohorts Collaborative International Assessment ...
Artículo
Evaluation of Suboptimal Peak Inspiratory Flow in Patients with Stable COPD
(MDPI, 2020)
Objective: Although the importance of assessing inspiratory flow in the selection of treatments for chronic obstructive pulmonary disease (COPD) is understood, evaluation of this factor is not yet widespread or standardized. ...