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Sobre la necesidad epistemológica de la investigación cualitativa en salud
(Sociedad Científica Española de Enfermería, 2014-05-15)
La sociedad occidental ha aceptado el concepto matemático de número sin ninguna crítica prácticamente desde la Escuela Pitagórica. Los trabajos de Georg Cantor sobre el concepto de infinito y sobre la teoría de conjuntos ...
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The absence of seroconversion after exposition to hepatitis C virus is not related to KIR-HLA genotype combinations (GEHEP-012 study)
(Elsevier, 2024)
Background & aims: It has been reported that specific killer-cell immunoglobulin-like receptors (KIRs) and HLA genotype combinations, such as KIR2DS4/HLA-C1 with presence of KIRDL2 or KIRDL3, homozygous KIRDL3/ HLA-C1 and ...
Artículo
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β-Lactam allergy delabeling is safe and saves costs in Primary Care
(Elsevier, 2024)
Objective: To determine whether the -lactam allergy delabeling was safe and cost-saving in Primary Care (PC) patients. Design: We have conducted a retrospective chart review of PC patients with -lactam allergy label ...
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Pseudomonas aeruginosa Community-Onset Bloodstream Infections: Characterization, Diagnostic Predictors, and Predictive Score Development—Results from the PRO-BAC Cohort
(MDPI, 2022)
Community-onset bloodstream infections (CO-BSI) caused by gram-negative bacilli are common and associated with significant mortality; those caused by Pseudomonas aeruginosa are associ- ated with worse prognosis and higher ...
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Levodopa-induced dyskinesia in Parkinson disease specifically associates with dopaminergic depletion in sensorimotor-related functional subregions of the striatum
(Lippincott, Williams & Wilkins, 2021)
Purpose: To determine whether the development of levodopa-induced dyskinesia (LID) in Parkinson disease (PD) specifically relates to dopaminergic depletion in sensorimotor-related subregions of the striatum. Methods: ...
Artículo
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Efficacy and safety of different antimicrobial DURATions for the treatment of Infections associated with Osteosynthesis Material implanted after long bone fractures (DURATIOM): Protocol for a randomized, pragmatic trial
(Public Library Science, 2023-05-22)
Background Infection associated with osteosynthesis material (IOM) is one of the most feared and challenging complications of trauma surgery and can cause significant functional loss, requiring multiple interventions and ...
Artículo
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Reply to letter: Erosive balanitis caused by Staphylococcus haemolyticus in a healthy, circumcised adult male
(2024)
The etiopathogenesis of lichen sclerosus (LS) is unknown and several factors are implicated. Chronic inflammation is one of the most reported [1]. The occlusive and moist environment under the foreskin may facilitate the ...
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Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii
(American Society for Microbiology, 2016-08)
LpxC inhibitors have generally shown poor in vitro activity against Acinetobacter baumannii. We show that the LpxC inhibitor PF-5081090 inhibits lipid A biosynthesis, as determined by silver staining and measurements of ...
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Impact of De-escalation on Prognosis of Patients With Bacteremia due to Enterobacteriaceae: A Post Hoc Analysis From a Multicenter Prospective Cohort
(Oxford University Press, 2019)
Background More data are needed about the safety of antibiotic de-escalation in specific clinical situations as a strategy to reduce exposure to broad-spectrum antibiotics. The aims of this study were to investigate ...
Artículo
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Activity of Host Antimicrobials against Multidrug-Resistant Acinetobacter baumannii Acquiring Colistin Resistance through Loss of Lipopolysaccharide
(American Society for Microbiology, 2014-05)
Acinetobacter baumannii can acquire resistance to the cationic peptide antibiotic colistin through complete loss of lipopolysaccharide (LPS) expression. The activities of the host cationic antimicrobials LL-37 and human ...