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Artículo
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Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function
(Elsevier, 2022)
Background & Aims: Autophagy-related gene 3 (ATG3) is an enzyme mainly known for its actions in the LC3 lipidation pro cess, which is essential for autophagy. Whether ATG3 plays a role in lipid metabolism or contributes ...
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Ewing Sarcoma Meets Epigenetics, Immunology and Nanomedicine: Moving Forward into Novel Therapeutic Strategies
(MDPI, 2022-11-07)
Ewing Sarcoma (EWS) is an aggressive bone and soft tissue tumor that mainly affects children, adolescents, and young adults. The standard therapy, including chemotherapy, surgery, and radiotherapy, has substantially improved ...
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Discovery of a small molecule inhibitor of human adenovirus capable of preventing escape from the endosome
(MDPI, 2021-02-05)
Human adenoviruses (HAdVs) display a wide range of tissue tropism and can cause an array of symptoms from mild respiratory illnesses to disseminated and life-threatening infections in immunocompromised individuals. ...
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5-year outcomes with cobimetinib plus vemurafenib in BRAFV600 mutation⇓positive advanced melanoma: extended follow-up of the coBRIM study
(American Association for Cancer Research, 2021)
Purpose: The randomized phase III coBRIM study (NCT01689519) demonstrated improved progression-free survival (PFS) and overall survival (OS) with addition of cobimetinib to vemurafenib compared with vemurafenib in patients ...
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Nuestra experiencia de ocho años en nutrición parenteral domiciliaria de pacientes adultos
(Arán Ediciones, 2020)
Introducción: la nutrición parenteral domiciliaria (NPD) es una técnica que permite incrementar la supervivencia de los pacientes con fallo intestinal. Objetivos: estudiar la evolución de la NPD en los últimos 8 años en ...
Artículo
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Effectiveness of fosfomycin trometamol as oral step-down therapy for bacteraemic urinary tract infections due to MDR Escherichia coli: a post hoc analysis of the FOREST randomized trial
(Oxford Academic, 2023)
Background Fosfomycin is a potentially attractive option as step-down therapy for bacteraemic urinary tract infections (BUTI), but available data are scarce. Our objective was to compare the effectiveness and safety of ...
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Artículo
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Topical iodine and thyroid gland. Do we have to take some caution?
(Elsevier, 2020)
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Factibilidad y resultados de un programa de rehabilitación cardiaca intensiva. Perspectiva del estudio aleatorizado MxM (Más por Menos)
(Doyma SL, 2021)
Introduccion y objetivos: Los programas de rehabilitacion cardiaca (PRC) engloban intervenciones encaminadas a mejorar el pronostico de la enfermedad cardiovascular influyendo en la condicin fısica, mental y social de ...
Artículo
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Approach to the Fatigue and Cellular Behavior of Superficially Modified Porous Titanium Dental Implants
(MDPI, 2022-05)
In this work, the fatigue and cellular performance of novel superficially treated porous titanium dental implants made up using conventional powder metallurgy and space-holder techniques (30 vol.% and 50 vol.%, both with ...