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Artículo
Rat Adrenal Chromaffin Cells Are Neonatal CO2 Sensors
(2005)
We studied the participation of adrenal medulla (AM) chromaffin cells in hypercapnic chemotransduction. Using amperometric recordings, we measured catecholamine (CAT) secretion from cells inAMslices of neonatal and adult ...
Artículo
Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats
(2003)
We studied the mechanisms underlying long-term functional recovery of hemiparkinsonian rats grafted intrastriatally with carotid body (CB) cell aggregates. Amelioration of their motor syndrome is a result of the trophic ...
Artículo
Functional and transcriptional induction of Aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α
(2011)
Aquaporin-1 (AQP1) is a water channel that is highly expressed in tissues with rapid O2 transport. It has been reported that this protein contributes to gas permeation (CO2, NO and O2) through the plasma membrane. We show ...
Artículo
Development of cytosolic hypoxia and hypoxia-inducible factor stabilization are facilitated by aquaporin-1 expression
(Elsevier, 2007)
O2 is essential for aerobic life, and the classic view is that it diffuses freely across the plasma membrane. However, measurements of O 2 permeability of lipid bilayers have indicated that it is much lower than previously ...
Tesis Doctoral
Quimiorrecepción del CO2 en la médula adrenal y facilitación de la permeabilidad a O2 por la acuaporina-1
(2007-02-02)
El desarrollo de esta Tesis se ha centrado en el estudio de los mecanismos celulares que permiten la quimiotransducción de O2 y CO2 en órganos como el cuerpo carotídeo y la médula adrenal. Teniendo en cuenta las evidencias ...