Search
Now showing items 201-210 of 549
Article
![With access to the full text Icon](/themes/idUS//images/acceso/opened_access.png)
A Small Domain in the N Terminus of the Regulatory a-Subunit Kv2.3 Modulates Kv2.1 Potassium Channel Gating
(1999)
Recent work has demonstrated the existence of regulatory K1 channel a-subunits that are electrically silent but capable of forming heterotetramers with other pore-forming subunits to modify their function. We have investigated ...
PhD Thesis
Article
![With access to the full text Icon](/themes/idUS//images/acceso/opened_access.png)
Cellular distribution of brain aquaporins and their contribution to cerebrospinal fluid homeostasis and hydrocephalus
(MDPI, 2022)
Brain aquaporins facilitate the movement of water between the four water compartments: blood, cerebrospinal fluid, interstitial fluid, and intracellular fluid. This work analyzes the expression of the four most abundant ...
Article
![With access to the full text Icon](/themes/idUS//images/acceso/opened_access.png)
High gamma activity distinguishes frontal cognitive control regions from adjacent cortical networks
(Elsevier, 2023)
Though the lateral frontal cortex is broadly implicated in cognitive control, functional MRI (fMRI) studies suggest fine-grained distinctions within this region. To examine this question electrophysiologically, we placed ...
Article
![With access to the full text Icon](/themes/idUS//images/acceso/opened_access.png)
Urocortin-1 Mediated Cardioprotection Involves XIAP and CD40-Ligand Recovery Role of EPAC2 and ERK12
(Public Library of Science, 2016)
Urocortin-1 (Ucn-1) is an endogenous peptide that protects heart from ischemia and reperfusion (I/R) injuries. Ucn-1 is known to prevent cardiac cell death, but its role in the transcription of specific genes related to ...
Chapter of Book
![With access to the full text Icon](/themes/idUS//images/acceso/opened_access.png)
La fisiología celular, los canales iónicos y la creación de una biofísica española
(Manuel Cortijo Mérida, 2011)
Article
![With access to the full text Icon](/themes/idUS//images/acceso/opened_access.png)
Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1
(Springer, 2021)
Genetic Alzheimer’s disease (AD) risk factors associate with reduced defensive amyloid β plaque-associated microglia (AβAM), but the contribution of modifiable AD risk factors to microglial dysfunction is unknown. In AD ...
Article
![With access to the full text Icon](/themes/idUS//images/acceso/opened_access.png)
Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab
(Nature Publishing Group, 2021)
Multiple myeloma (MM) is incurable, so there is a significant unmet need for effective therapy for patients with relapsed or refractory disease. This situation has not changed despite the recent approval of the anti-CD38 ...
Article
![With access to the full text Icon](/themes/idUS//images/acceso/opened_access.png)
Presynaptic Mitochondria Communicate With Release Sites for Spatio-Temporal Regulation of Exocytosis at the Motor Nerve Terminal
(Frontiers Research Foundation, 2022)
Presynaptic Ca2+ regulation is critical for accurate neurotransmitter release, vesicle reloading of release sites, and plastic changes in response to electrical activity. One of the main players in the regulation of ...
PhD Thesis
![With access to the full text Icon](/themes/idUS//images/acceso/opened_access.png)
Fisiopatología de la HSA: alteraciones en la funcionalidad vascular en un modelo animal de HSA y cambios en las células mononucleares de sangre periférica de pacientes
(2022-01-17)
Los cambios legislativos que se han producido en la Unión Europea por la aparición de la Directiva UE 2014-24 sobre contratación pública, han transformado el paradigma en el control de costes de la edificación pública. ...