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Mostrando ítems 1-10 de 24
Artículo
Preparation, characterization and evaluation of the anti-inflammatory activity of epichlorohydrin-β-cyclodextrin/curcumin binary systems embedded in a pluronic® /hyaluronate hydrogel
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Curcumin (Cur) is an anti-inflammatory polyphenol that can be complexed with polymeric cyclodextrin (CD) to improve solubility and bioavailability. The aim of the present work was to prepare a CurCD hydrogel to treat ...
Artículo
Synergistic effect of acetazolamide-(2-hydroxy)propyl β-cyclodextrin in timolol liposomes for decreasing and prolonging intraocular pressure levels
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
The purpose of this study was to design, for the first time, a co-loaded liposomal formulation (CLL) for treatment of glaucoma including timolol maleate (TM) in the lipid bilayer and acetazolamide (Acz)-(2-hydroxy)propyl ...
Artículo
Cholesterol levels affect the performance of aunps-decorated thermo-sensitive liposomes as nanocarriers for controlled doxorubicin delivery
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Stimulus-responsive liposomes (L) for triggering drug release to the target site are particularly useful in cancer therapy. This research was focused on the evaluation of the effects of cholesterol levels in the performance ...
Artículo
Human neural stem cells for cell-based medicinal products
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Neural stem cells represent an attractive tool for the development of regenerative therapies and are being tested in clinical trials for several neurological disorders. Human neural stem cells can be isolated from the ...
Artículo
Avances en las formulaciones de los antisépticos
(Universidad de Granada, 2021)
Objetivo: Revisar nuevas formulaciones antisépticas que minimicen los inconvenientes de las formulaciones convencionales y mejoren la efectividad los tratamientos actualmente usados. Metodología: Se ha realizado una ...
Tesis Doctoral
Estudio y análisis jurídico de la Ley 17/04 relativa al Código del Medicamento y de la Farmacia en Marruecos
(2020-05-29)
La memoria de esta tesis doctoral, que se expone a continuación, trata de analizar la Ley 17-04 relativa al Código del Medicamento y de la Farmacia, considerada hoy en día como el texto legislativo de mayor importancia, ...
Artículo
Nanotechnologies for the delivery of biologicals: Historical perspective and current landscape
(Elsevier, 2021)
Biological macromolecule-based therapeutics irrupted in the pharmaceutical scene generating a great hope due to their outstanding specificity and potency. However, given their susceptibility to degradation and limited ...
Artículo
A Biodegradable Copolyester, Poly(butylene succinate-co-ε-caprolactone), as a High Efficiency Matrix Former for Controlled Release of Drugs
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
A biodegradable copolyester, poly(butylene succinate-co-ε-caprolactone) (PBS_CL), was used for first time as an excipient for pharmaceutical dosage forms using direct compression and hot processing techniques (ultrasound-assisted ...
Artículo
The polypill: An effective approach to increasing adherence and reducing cardiovascular event risk
(Oxford University Press, 2020-08)
Background Despite a wide range of medications being available for the prevention of cardiovascular events such as stroke, myocardial infarction and mortality in both a primary and secondary setting, patient adherence to ...
Tesis Doctoral
Diseño de sistemas nanoparticulares lipídicos para co-administración de teofilina y ciprofloxacino en el tratamiento de la fibrosis quística
(2020-02-14)
La fibrosis quística (FQ) es una enfermedad causada por una mutación de un gen que codifica el canal clorhídrico transmembrana denominado regulador de la conductancia transmembrana de la FQ (CFTR), que regula el transporte ...