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Artículo
Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs
(Wolters Kluwer Health, 2010)
Oxidative therapy is a relatively new anticancer strategy based on the induction of high levels of oxidative stress, achieved by increasing intracellular reactive oxygen species (ROS) and/or by depleting the ...
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Mature Cystic Teratoma of the Lung With a Somatic-Like Malignant Component in a Patient With Testicular Germ-Cell Tumor
(Sociedad Española de Neumología y Cirugía Torácica SEPAR, 2018-12)
In urological oncology, the diagnosis of teratoma with a somatic-like malignant component refers to the presence of a malignant neoplasm, e.g. carcinoma or sarcoma, either within a teratoma of the genital tract (usually ...
Artículo
Postnatal Fate of the Ultimobranchial Remnants in the Rat Thyroid Gland
(Wiley Periodicals, Inc., 2013-07)
The ultimobranchial follicles (UBFs) areconsidered embryonic remnants from the ultimobran-chial body (UBB). They are follicular structures thatvary in size and appearance depending on the age of therat. ...
Artículo
Collision tumour involving a rectal gastrointestinal stromal tumour with invasion of the prostate and a prostatic adenocarcinoma
(BMC, 2012-10-30)
Background: Gastrointestinal stromal tumours (GISTs) are the most common primary mesenchymal neoplasia in the gastrointestinal tract, although they represent only a small fraction of total gastrointestinal malignancies ...
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Artículo
Ciclos de mejora docente integrados en Anatomía Patológica: ¿primer paso hacia una enseñanza integrada?
(Universidad de Sevilla, 2018)
Nuestra hipótesis es que el aprendizaje de los alumnos mejoraría si se integrasen contenidos de diversas asignaturas y se adelantasen algunos contenidos clínicos al comienzo del Grado de Medicina. Para llevar a cabo ...
Artículo
Influence of high glucose and advanced glycation end-products (ages) levels in human osteoblast-like cells gene expression
(2016)
Background: Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporotic fracture. Several factors have been identified as being potentially responsible for this risk, such as alterations in bone ...
Artículo
Immunohistochemical profiling of the ultimobranchial remnants in the rat postnatal thyroid gland
(Wiley Periodicals, Inc., 2017-05-02)
Ultimobranchial (UB) remnants are a constant presence in the thyroid throughout rat postnatal life; however, the difficulty in identifying the most immature forms from the surrounding thyroid tissue prompted us to search ...
Artículo
Amitriptyline down-regulates coenzyme Q10 biosynthesis in lung cancer cells
(Elsevier, 2017)
Amitriptyline, a tricyclic antidepressant, has been proposed as an antitumoral drug in oxidative therapy. Its pro-apoptotic effects, mediated by high reactive oxygen species generation, have been already described. In ...
Artículo
Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients
(Impact Journals, 2017)
Wilms tumour (WT) is the most common renal tumour in children. Most WT patients respond to chemotherapy, but subsets of tumours develop resistance to chemotherapeutic agents, which is a major obstacle in their successful ...