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Artículo
Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus
(Springer, 2012)
Dystrophic neurites associated with amyloid plaques precede neuronal death and manifest early in Alzheimer’s disease (AD). In this work we have characterized the plaque-associated neuritic pathology in the hippocampus ...
Artículo
Monocyte-derived Cells Invade Brain Parenchyma and Amyloid Plaques in Human Alzheimer’s Disease Hippocampus
(Springer Nature, 2023)
Microglia are brain-resident myeloid cells and play a major role in the innate immune responses of the CNS and the pathogenesis of Alzheimer's disease (AD). However, the contribution of nonparenchymal or brain-infiltrated ...