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Artículo
Mitochondrial toxins and neurodegenerative diseases
(IMR Press, 2007)
The selective loss of a particular subset of neurons is a common feature of neurodegenerative disorders. A failure in respiratory chain complex activities in mitochondria seems to be a causative factor. The aim of this ...
Artículo
Oxidative stress is increased in critically ill patients according to antioxidant vitamins intake, independent of severity: A cohort study
(Springer Science + Business Media, 2006)
Critically ill patients suffer from oxidative stress caused by reactive oxygen species (ROS) and reactive nitrogen species (RNS). Although ROS/RNS are constantly produced under normal circumstances, critical illness can ...
Artículo
Impairment of mineralocorticoid receptor (MR)-dependent biological response by oxidative stress and aging
(American Society for Biochemistry and Molecular Biology, 2002)
Acute and chronic treatments of mice with the gluta- thione-depleting agent, L-buthionine-(SR)-sulfoximine (BSO), impaired the mineralocorticoid receptor (MR)- dependent biological response by inhibiting aldoster- one ...
Artículo
Stress Increases Vulnerability to Inflammation in the Rat Prefrontal Cortex
(Society for Neuroscience, 2006)
Inflammation could be involved in some neurodegenerative disorders that accompany signs of inflammation. However, because sensitivity to inflammation is not equal in all brain structures, a direct relationship is not clear. ...