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- Bioquímica y Biología Molecular
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Listar Artículos (Bioquímica y Biología Molecular) por autor "Rodhe, Johanna"
Mostrando ítems 1-5 de 5
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Artículo
Caspase-8 inhibition represses initial human monocyte activation in septic shock model
Oliva Martín, María José; Sánchez Abarca, Luis Ignacio; Rodhe, Johanna; Carrillo Jiménez, Alejandro; Vlachos, Pinelopi; Herrera Carmona, Antonio José; García Quintanilla, Alberto; Caballero Velázquez, Teresa; Venero Recio, José Luis (Impact Journals, 2016)In septic patients, the onset of septic shock occurs due to the over-activation of monocytes. We tested the therapeutic ...
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Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model
Kavanagh, Edel T.; Burguillos García, Miguel Ángel; Carrillo Jiménez, Alejandro; Oliva Martín, María José; Santiago Pavón, Martiniano; Rodhe, Johanna; Joseph, Bertrand; Venero Recio, José Luis (Impact Journals, LLC, 2015)Increasing evidence involves sustained pro-inflammatory microglia activation in the pathogenesis of different neurodegenerative ...
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Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype
Shen, Xianli; Burguillos García, Miguel Ángel; Osman, Ahmed Mohamed; Frijhoff, Jeroen; Carrillo Jiménez, Alejandro; Kanatani, Sachie; Augsten, Martin; Saidi, Dalel; Rodhe, Johanna; Kavanagh, Edel T.; Venero Recio, José Luis; Joseph, Bertrand (Springer Nature, 2016-10-19)Glioma cells recruit and exploit microglia (the resident immune cells of the brain) for their proliferation and invasion ...
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Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia
Kavanagh, Edel T.; Rodhe, Johanna; Burguillos García, Miguel Ángel; Venero Recio, José Luis; Joseph, Bertrand (Nature Publishing Group, 2014)The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity ...
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Spatio-temporal activation of caspase-8 in myeloid cells upon ischemic stroke
Rodhe, Johanna; Burguillos García, Miguel Ángel; Martínez de Pablos, Rocío; Kavanagh, Edel T.; Persson, Annette; Englund, Elisabet; Venero Recio, José Luis (BioMed Central, 2016)Ischemic stroke (caused by thrombosis, embolism or vasoconstriction) lead to the recruitment and activation of immune cells ...