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Artículo
Temporal expression patterns of the melatoninergic system in the human thymus of children
(Elsevier BV, 2019)
Objectives: To obtain greater knowledge of the extra-pineal sources of melatonin during development, the amount of indolamine and the expression levels of the last two enzymes involved in its biosynthesis, Arylalkylamine ...
Artículo
Artículo
Effect of homeostatic T-cell proliferation in the vaccine responsiveness against influenza in elderly people
(BioMed Central Ltd., 2019)
Background: Seasonal influenza virus infection is a significant cause of morbimortality in the elderly. However, there is poor vaccine efficacy in this population due to immunosenescence. We aimed to explore several homeostatic ...
Artículo
Artículo
Peripheral CD39-expressing T regulatory cells are increased and associated with relapsing-remitting multiple sclerosis in relapsing patients
(Nature Research, 2019-02-19)
CD39, an ectonucleotidase that hydrolyses pro-infammatory ATP, is a marker of highly active and suppressive T regulatory cells (Tregs). Although CD39 has a role in Treg suppression and might be important in the control ...
Artículo
Melatonin-synthesizing enzymes and melatonin receptor in rat thyroid cells
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2012-11)
Melatonin is an indoleamine with a wide spectrum of biological activities other than transmitting photoperiod information, including antioxidant, oncostatic, anti-aging and immunomodulatory properties. Although melatonin ...