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Artículo
Dietary fatty acids and lipoproteins on progression of age-related macular degeneration
(CSIC, 2017)
Age-related macular degeneration (AMD) is a medical condition of central loss vision and blindness. Numerous studies have revealed that changes on certain dietary fatty acids (FAs) could have useful for AMD management. ...
Artículo
Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells
(Elsevier, 2017)
The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative stress and inflammation were investigated in TNF-α-activated human endothelial cells. HTyr sulfate ...
Artículo
Tyrosol and its metabolites as antioxidative and anti-inflammatory molecules in human endothelial cells
(Royal Society of Chemistry, 2017)
Tyrosol (Tyr) is a phenolic compound found in virgin olive oil. After ingestion, Tyr undergoes extensive first pass intestinal/hepatic metabolism. However, knowledge about the biological effects of Tyr metabolites is scarce. ...
Artículo
Dietary fatty acids on aortic root calcification in mice with metabolic syndrome
(Royal Society of Chemistry, 2017)
Metabolic syndrome (MetS) is associated with obesity, dyslipidemia, type 2 diabetes, and chronic low-grade inflammation. The aim of this study was to determine the role of high-fat low-cholesterol diets (HFLCDs) rich in ...
Artículo
Olive oil and postprandial hyperlipidemia: Implications for atherosclerosis and metabolic syndrome
(Royal Society of Chemistry, 2016)
Olive oil is the primary source of fat in the Mediterranean diet, which is associated with a significant improvement in health status, as measured by reduced mortality from several chronic diseases. The current pandemic ...
Artículo
Squalene targets pro- and anti-inflammatory mediators and pathways to modulate over-activation of neutrophils, monocytes and macrophages
(Elsevier, 2015)
Squalene is a natural triterpene consumed as an integral part of the human diet. Increasing evidence demonstrates that squalene has antioxidant, cardioprotective and anti-carcinogenic activities. Nevertheless, its ...
Artículo
Pharmacological effects of mitraphylline from Uncaria tomentosa in primary human monocytes: Skew toward M2 macrophages
(Elsevier, 2015)
Ethnopharmacological relevance Uncaria tomentosa (Willdenow ex Roemer & Schultes) DC. (Rubiaceae) is a Peruvian thorny liana, commonly known as "cat's claw", and traditionally used in folk medicine to deal with several ...
Artículo
Olive oil, compared to a saturated dietary fat, has a protective role on atherosclerosis in niacin-treated mice with metabolic syndrome
(Elsevier, 2016)
We aimed to investigate the impact of high-fat low-cholesterol diets rich in saturated fatty acids (HFLCD-SFAs), monounsaturated FAs (HFLCD-MUFAs) or MUFAs + omega-3 long-chain polyunsaturated FAs (HFLCD-PUFAs) in combination ...