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Listar Bioquímica Médica y Biología Molecular e Inmunología por autor "Sánchez Margalet, Víctor"
Mostrando ítems 21-40 de 55
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Artículo
Leptin action in normal and pathological pregnancies
Pérez Pérez, Antonio; Toro, Ayelén; Vilariño García, Teresa; Maymó, Julieta L.; Guadix, Pilar; Varone, C.; Sánchez Margalet, Víctor (2018)Leptin is now considered an important signalling molecule of the reproductive system, as it regulates the production of ...
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Artículo
Leptin and Nutrition in Gestational Diabetes
Pérez Pérez, Antonio; Vilariño García, Teresa; Guadix, Pilar; Dueñas, José L.; Sánchez Margalet, Víctor (MPDI, 2020-07-02)Leptin is highly expressed in the placenta, mainly by trophoblastic cells, where it has an important autocrine trophic ...
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Artículo
Leptin, both bad and good actor in cancer
Jiménez Cortegana, Carlos; López-Saavedra, Ana; Sánchez Jiménez, Flora; Pérez Pérez, Antonio; Castiñeiras Fernández, Jesús; Virizuela-Echaburu, Juan A.; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (MDPI, 2021)Leptin is an important regulator of basal metabolism and food intake, with a pivotal role in obesity. Leptin exerts many ...
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Tesis Doctoral
Leptina. Estudio sobre el estrés oxidativo y la vía de señalización celular en monocitos de pacientes VIH positivos
Sánchez Pozo, María Cristina (2006-06-13)El descubrimiento de la leptina ha arrojado luz en la compleja biología del tejido adiposo. En contra de la visión previa ...
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Artículo
Low levels of granulocytic myeloid-derived suppressor cells may be a good marker of survival in the follow-up of patients with severe COVID-19
Jiménez Cortegana, Carlos; Sánchez Jiménez, Flora; Pérez Pérez, Antonio; Álvarez, Nerissa; Sousa, Alberto; Cantón Bulnes, María Luisa; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (Frontiers Media S.A., 2022)Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a disease (coronavirus disease 2019, ...
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Artículo
Lower Survival and Increased Circulating Suppressor Cells in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma with Deficit of Vitamin D Levels Using R-GDP Plus Lenalidomide (R2-GDP): Results from the R2-GDP-GOTEL Trial
Jiménez Cortegana, Carlos; Sánchez Martínez, Pilar M.; Palazón Carrión, Natalia; Nogales Fernández, Esteban; Henao Carrasco, Fernando Manuel; García Sancho, Alejandro Martín; Rueda, Antonio; Provencio, Mariano; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (MDPI, 2021-09-15)The search of prognostic factors is a priority in diffuse large B-cell lymphoma (DLBCL) due to its aggressiveness. We ...
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Tesis Doctoral
Mecanismos de inmunomodulación de la leptina en células T Jurkat
Fernández Riejos, Patricia (2006-07-04)La leptina no es sólo una hormona del tejido adiposo que regula la ingesta y el gasto energético a nivel central, sino que ...
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Artículo
Myeloid-derived suppressor cells and vaccination against pathogens
Prochetto, Estefanía; Borgna, Eliana; Jiménez Cortegana, Carlos; Sánchez Margalet, Víctor; Cabrera, Gabriel (Frontiers Media, 2022-09-29)It is widely accepted that the immune system includes molecular and cellular components that play a role in regulating and ...
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Artículo
New insights into the role of the immune microenvironment in breast carcinoma
Nieto García, María Adoración; Sánchez Margalet, Víctor; Alba Conejo, Emilio; Ruiz Borrego, Manuel; Cruz Merino, Luis de la; Codes Manuel de Villena, Manuel; Henao Carrasco, Fernando Manuel; Vallejo Benítez, Ana; Barco Sánchez, Antonio; Nogales Fernández, Esteban; Brugal Molina, Javier; Martínez Peinado, Antonio; Grueso López, Ana; Casares Lagar, Noelia; Ibáñez Martínez, José (2013)Recently, immune edition has been recognized as a new hallmark of cancer. In this respect, some clinical trials in breast ...
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Artículo
Nutrients and Dietary Approaches in Patients with Type 2 Diabetes Mellitus and Cardiovascular Disease: A Narrative Review
Jiménez Cortegana, Carlos; Iglesias, Pedro; Ribalta, Josep; Vilariño García, Teresa; Montañez, Laura; Arrieta, Francisco; Durán García, Santiago; Sánchez Margalet, Víctor (MDPI, 2021-11-19)Cardiovascular disease (CVD) is the most common cause of morbidity and mortality in developed countries. The prevalence ...
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Artículo
Obesity and Breast Cancer: Role of Leptin
Sánchez Jiménez, Flora; Pérez Pérez, Antonio; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (2019-07-18)Obesity-related breast cancer is an important threat that affects especially post-menopausal women. The link between ...
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Artículo
Obesity and Risk for Lymphoma: Possible Role of Leptin
Jiménez Cortegana, Carlos; Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; Zapata, Fernando; Palazón Carrión, Natalia; Sánchez León, María Luisa; Tami, Malika; Pérez Pérez, Antonio; Sánchez Jiménez, Flora; Vilariño García, Teresa; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (MDPI, 2022-12-08)Obesity, which is considered a pandemic due to its high prevalence, is a risk factor for many types of cancers, including ...
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Artículo
Obesity as a Risk Factor for Dementia and Alzheimer’s Disease: The Role of Leptin
Flores Cordero, Juan Antonio; Pérez Pérez, Antonio; Jiménez Cortegana, Carlos; Alba Jiménez, Gonzalo; Flores-Barragán, Alfonso; Sánchez Margalet, Víctor (MDPI AG, 2022)Obesity is a growing worldwide health problem, affecting many people due to excessive saturated fat consumption, lack of ...
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Artículo
Pancreastatin activates protein-kinase-C by stimulating the formation of 1,2-diacylglycerol in rat hepatocytes
Goberna Ortiz, Raimundo; Sánchez Margalet, Víctor; Lucas, Miguel (1994) -
Tesis Doctoral
Papel de la leptina y su resistencia en el síndrome de ovario poliquístico y la diabetes gestacional
Vilariño García, Teresa (2021-10-06)La resistencia a la insulina y el síndrome metabólico al que se asocia es un problema sociosanitario de primer nivel. En ...
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Tesis Doctoral
Papel de la pancreastatina en la homeostasis de la glucosa
Sánchez Margalet, Víctor (1991-07-05)La pancreastatina, un péptido de 49 aminoacidos, fue Aislada del páncreas porcino en diciembre de 1986, se Encuentra ...
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Artículo
Pembrolizumab in combination with gemcitabine for patients with HER2-negative advanced breast cancer: GEICAM/2015–04 (PANGEA-Breast) study
Cruz Merino, Luis de la; Gion, M.; Cruz, J.; Alonso-Romero, J. L.; Quiroga, V.; Moreno, F.; Jiménez Cortegana, Carlos; Sánchez Margalet, Víctor; Rojo, F. (BMC, 2023)Background: We evaluated a new chemoimmunotherapy combination based on the anti-PD1 monoclonal antibody pembrolizumab and ...
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Artículo
Pembrolizumab Plus Gemcitabine in the Subset of Triple-Negative Advanced Breast Cancer Patients in the GEICAM/2015-04 (PANGEA-Breast) Study
Cruz Merino, Luis de la; Gion, María; Cruz Jurado, Josefina; Quiroga, Vanesa; Andrés, Raquel; Moreno, Fernando; Jiménez Cortegana, Carlos; Sánchez Margalet, Víctor; Rojo, Federico (MDPI, 2021-10-29)The PANGEA-Breast trial evaluated a new chemo-immunotherapeutic combination that would synergistically induce long-term ...
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Artículo
Possible Role of Leptin in Atopic Dermatitis: A Literature Review
Jiménez Cortegana, Carlos; Ortiz García, Germán; Serrano, Amalia; Moreno Ramírez, David; Sánchez Margalet, Víctor (MDPI, 2021-11-05)Atopic dermatitis (AD) is the most frequent chronic inflammatory skin disease, and its incidence has been rapidly increasing ...
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Tesis Doctoral
Prevalencia del déficit de vitamina D y significado pronóstico en pacientes ancianos ingresados por síndrome coronario agudo.
García Guerrero, Alberto (2018-06-19)Introducción: La deficiencia de vitamina D (25-OH-VITD) se ha relacionado con la génesis de la ateroesclerosis coronaria ...