Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja: Envíos recientes
Mostrando ítems 181-200 de 282
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Electronic and structural effects of low-hapticity coordination of arene rings to transition metals
(American Chemical Society, 2014)A DFT computational study and a structural analysis of the coordination of arenes to transition metals in low -hapticity ...
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Antileishmanial activity of sp2-iminosugar derivatives
(Royal Society of Chemistry, 2015)A series of sp2-iminosugar-type glycomimetics bearing S-linked pseudoglycoside substituents (sulfide, sulfoxide and sulfone ...
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Trehalose- and Glucose-Derived Glycoamphiphiles: Small-Molecule and Nanoparticle Toll-Like Receptor 4 (TLR4) Modulators
(American Chemical Society, 2014)An increasing number of pathologies have been linked to Toll-like receptor 4 (TLR4) activation and signaling, therefore ...
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Reactivity of TpMe2-containing hydride-iridafurans with alkenes, alkynes, and H2
(American Chemical Society, 2014)The TpMe2-containing hydride-iridafurans 2a,b (TpMe2 = hydrotris(3,5-dimethylpyrazolyl)borate) cleanly reacted with ethylene ...
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Formation of β-Metallanaphthalenes by the Coupling of a Benzo-Iridacyclopentadiene with Olefins
(American Chemical Society, 2015)We have synthesized a new type of metallaaromatic complexes, namely the hydride-β-iridanaphthalenes TpMe2tiebar above ...
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Conformationally-locked N -glycosides: Exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher disease
(Elsevier, 2015)Pyranoid-type glycomimetics having a cis-1,2-fused glucopyranose–2-alkylsulfanyl-1,3-oxazoline (Glc-PSO) structure exhibit ...
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Antioxidant activity of alkyl gallates and glycosyl alkyl gallates in fish oil in water emulsions: Relevance of their surface active properties and of the type of emulsifier
(Elsevier, 2015)The antioxidant activity of gallic acid and a series of alkyl gallates (C4-C18) and glycosylated alkyl gallates (C4-C18) ...
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Oxidative stress is tightly regulated by cytochrome c phosphorylation and respirasome factors in mitochondria
(National Academy of Sciences, 2018)Respiratory cytochrome c has been found to be phosphorylated at tyrosine 97 in the postischemic brain upon neuroprotective ...
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Glucose conjugation of anti-HIV-1 oligonucleotides containing unmethylated CpG motifs reduces their immunostimulatory activity
(John Wiley & Sons, 2015)Antisense oligodeoxynucleotides (ODNs) are short synthetic DNA polymers complementary to a target RNA sequence. They are ...
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Ruthenium(II) Complexes Containing Lutidine-derived Pincer CNC Ligands: Synthesis, Structure and Catalytic Hydrogenation of C=N bonds
(Wiley-Blackwell, 2015)A series of Ru complexes containing lutidine‐derived pincer CNC ligands have been prepared by transmetalation with the ...
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Cell uptake mechanisms of glycosylated cationic pDNA-cyclodextrin nanoparticles
(Royal Society of Chemistry, 2015)The incorporation of carbohydrate functional elements in the architecture of polycationic amphiphilic cyclodextrins (paCDs) ...
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Synthesis and Reactivity toward H2 of (h5- C5Me5)Rh(III) Complexes with Bulky Aminopyridinate Ligands
(American Chemical Society, 2015)Electrophilic, cationic Rh(III) complexes of composition [(η5-C5Me5)Rh(Ap)]+, (1+), were prepared by reaction of ...
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Asymmetric Hydrogenation of 1-alkyl and 1-aryl vinyl benzoates: a broad scope procedure for the highly enantioselective synthesis of 1-substituted ethyl benzoates
(2014)The enantioselective hydrogenation of enol esters of formula CH2=C(OBz)R with rhodium catalysts based on phosphine-phosphite ...
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Harmonized tuning of nucleic acid and lectin binding properties with multivalent cyclodextrins for macrophage-selective gene delivery
(Royal Society of Chemistry, 2015)Polycationic amphiphilic cyclodextrins (paCDs) have been shown to behave as efficient non-viral gene carriers paralleling ...
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Analysis of the expression of tachykinins and tachykinin receptors in the rat uterus during early pregnancy
(Society for the Study of Reproduction, 2015)The peptides of the tachykinin family participate in the regulation of reproductive function acting at both central ...
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Altered glutamyl-aminopeptidase activity and expression in renal neoplasms
(BioMed Central, 2014)[Background] Advances in the knowledge of renal neoplasms have demonstrated the implication of several proteases in their ...
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Unprecedented Inhibition of Glycosidase-Catalyzed Substrate Hydrolysis by Nanodiamond-Grafted O-Glycosides
(Royal Society of Chemistry, 2015)We report herein the unprecedented finding that α-O-glucosides and also α-O-mannosides, when conjugated on nanodiamond ...
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Detection and Quantitative Analysis of Two Independent Binding Modes of a Small Ligand Responsible for DC-SIGN Clustering
(Royal Society of Chemistry, 2015)DC-SIGN (dendritic cell-specific ICAM-3 grabbing non-integrin) is a C-type lectin receptor (CLR) present, mainly in dendritic ...
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Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection
(Nature Publishing Group, 2016)The use of multivalent carbohydrate compounds to block cell-surface lectin receptors is a promising strategy to inhibit ...
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Conformationally-Locked C-Glycosides: Tuning Aglycone Interactions for Optimal Cheperone Behaviour in Gaucher Fibroblasts
(Royal Society of Chemistry, 2016)A series of conformationally locked C-glycosides based on the 3-aminopyrano[3,2-b]pyrrol-2(1H)-one (APP) scaffold has been ...