Listar Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja por título
Mostrando ítems 218-237 de 276
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Silver-free gold-catalyzed heterocyclizations through intermolecular H-bonding activation.
(AMER Chemical Soc, 2023-01-27)Modulable monosulfonyl squaramides have been shown to exert activation of gold(I) chloride complexes through H-bonding in ...
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sp2-Iminosugar Azobenzene O-glycosides: Light-sensitive Glycosidase Inhibitors with Unprecedented Tunability and Switching Factors
(Elsevier, 2024)The conventional approach to developing light-sensitive glycosidase activity regulators, involving the combination of a ...
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sp2-Iminosugar Glycolipids as Inhibitors of Lipopolysaccharide-mediated Human Dendritic Cell Activation in Vitro and of Acute Inflammation in Mice in Vivo
(Elsevier, 2019)Glycolipid mimetics consisting of a bicyclic polyhydroxypiperidine-cyclic carbamate core and a pseudoanomeric hydrophobic ...
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sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease
(Taylor & Francis, 2022)The late-onset form of Tay-Sachs disease displays when the activity levels of human β-hexosaminidase A (HexA) fall below ...
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Speeding-up the Determination of Protein-Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR)
(American Chemical Society, 2024-01-02)STD NMR spectroscopy is a powerful ligand-observed NMR tool for screening and characterizing the interactions of small ...
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Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis
(American Chemical Society, 2020)The first examples of iminosugar-type 2-deoxy(thio)glycoside mimetics are reported. The key step is the activation of a ...
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Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48
(National Academy of Sciences, 2017)Regulation of mitochondrial activity allows cells to adapt to changing conditions and to control oxidative stress, and ...
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Structural diversity and magnetic properties of copper(ii) quinaldinate compounds with amino alcohols
(Royal Society of Chemistry, 2022)The reactions between [Cu(quin)2(H2O)] (quin− = the anionic form of quinoline-2-carboxylic acid) and a series of aliphatic ...
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Structural insights into the intracellular region of the human magnesium transport mediator CNNM4
(Multidisciplinary Digital Publishing Institute (MDPI), 2019)The four member family of “Cyclin and Cystathionine β-synthase (CBS) domain divalent metal cation transport mediators”, ...
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Sulforaphane homologues: Enantiodivergent synthesis of both enantiomers, activationof the Nrf2 transcription factor and selective cytotoxic activity
(Elsevier, 2014)Reported is an enantiodivergent approach for the synthesis of both enantiomers of sulforaphane (SFN) homologues with ...
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SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
(Elsevier, 2024-03-26)The posttranslational modification of proteins critically influences many biological processes and is a key mechanism that ...
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SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer
(Elsevier, 2019)BACKGROUND: Even though liver kinase B1 (LKB1) is usually described as a tumor suppressor in a wide variety of tissues, ...
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Surface-Active Properties of Lipophilic AntioxidantsTyrosol and Hydroxytyrosol Fatty Acid Esters: A PotentialExplanation for the Nonlinear Hypothesis of the AntioxidantActivity in Oil-in-Water Emulsions
(American Chemical Society, 2001)Our group has recently observed a nonlinear tendency in antioxidant capacity of different hydroxytyrosol fatty acid esters ...
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Synthesis and characterization of enantiopure chiral NH2/SO palladium complexes
(Royal Society of Chemistry, 2023)A series of enantiopure chiral NH2/SO palladium complexes have been synthesised with high yields by treating the corresponding ...
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Synthesis and reactivity of half-sandwich (η 5 -C 5 Me 5 )Ir(iii) complexes of a cyclometallated aryl phosphine ligand
(Royal Society of Chemistry, 2011)Reaction of the Ir(iii) dimer [(η 5 -C 5 Me 5 )IrCl 2 ] 2 with PMeXyl 2 (Xyl = 2,6-C 6 H 3 Me 2 ), in the presence of the ...
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Synthesis and Reactivity of Nickel an Palladium Fluoride Complexes with PCP Pincer Ligands. A NMR-Based Assessment of Electron-Donating Properties of Fluoride and Other Monoanionic Ligands
(American Chemical Society, 2012)A series of complexes of the type [(iPrPCP)M-L] (M = Ni, Pd), containing the 2,6-bis(diisopropylphosphinomethyl)phenyl ...
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Synthesis and reactivity studies of cationic Ir(III) alkylidines. α-hydride abstraction reactions
(Sociedad Química de México, 2017)The chemistry of late transition metal alkylidenes [M=CR2], where R is H a hydrocarbyl group, have attracted widespread ...
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Synthesis and Reactivity toward H2 of (h5- C5Me5)Rh(III) Complexes with Bulky Aminopyridinate Ligands
(American Chemical Society, 2015)Electrophilic, cationic Rh(III) complexes of composition [(η5-C5Me5)Rh(Ap)]+, (1+), were prepared by reaction of ...
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Synthesis and structural characterization of a binuclear iridium complex with bridging, bidentate N-heterocyclic carbene coordination of 2, 2 ':6 ', 2''-terpyridine
(Royal Society of Chemistry, 2009)Thermal activation of terpyridine in the presence of an unsaturated Ir(III) fragment stabilized by a hydrotris(pyrazolyl) borate ...
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Synthesis and structure of mixed carboxylate-aminopyridinate and -amidinate complexes of dimolybdenum and ditungsten
(Elsevier, 2015)We describe in this paper the synthesis and structural characterization of dimolybdenum and ditungsten complexes with MM ...