Now showing items 1-10 of 26
An evolutionary analysis of the reaction mechanisms of photosystem I reduction by cytochrome c6 and plastocyanin [Article]
Photosystem I reduction by the soluble metalloproteins cytochrome c6 and plastocyanin, which are alternatively synthesized by some photosynthetic organisms depending on the relative availability of copper and iron, has ...
Molecular basis of FIR-mediated c-myc transcriptional control [Article]
(Nature Research, 2010)
The far upstream element (FUSE) regulatory system promotes a peak in the concentration of c-Myc during cell cycle. First, the FBP transcriptional activator binds to the FUSE DNA element upstream of the c-myc promoter. Then, ...
Nitration of tyrosine 74 prevents human cytochrome c to play a key role in apoptosis signaling by blocking caspase-9 activation [Article]
Tyrosine nitration is one of the most common post-transcriptional modifications of proteins, so affecting their structure and function. Human cytochrome c, with five tyrosine residues, is an excellent case study as it is ...
The sequence selectivity of KSRP explains its flexibility in the recognition of the RNA targets [Article]
(Oxford University Press, 2008)
K-homology (KH) splicing regulator protein (KSRP) is a multi-domain RNA-binding protein that regulates different steps of mRNA metabolism, from mRNA splicing to mRNA decay, interacting with a broad range of RNA sequences. ...
Cytochrome c1 exhibits two binding sites for cytochrome c in plants [Article]
n plants, channeling of cytochrome c molecules between complexes III and IV has been purported to shuttle electrons within the supercomplexes instead of carrying electrons by random diffusion across the intermembrane bulk ...
New Arabidopsis thaliana cytochrome c partners: A look into the elusive role of cytochrome c in programmed cell death in plants [Article]
(American Society for Biochemistry and Molecular Biology, 2013)
Programmed cell death is an event displayed by many different organisms along the evolutionary scale. In plants, programmed cell death is necessary for development and the hypersensitive response to stress or pathogenic ...
The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets [Article]
(Taylor & Francis, 2014)
Human antigen R (HuR) is a 32 kDa protein with 3 RNA Recognition Motifs (RRMs), which bind to Adenylate and uridylate Rich Elements (AREs) of mRNAs. Whereas the N-terminal and central domains (RRM1 and RRM2) are essential ...
The dynamic complex of cytochrome c6 and cytochrome f studied with paramagnetic NMR spectroscopy [Article]
(Elsevier B.V., 2014)
The rapid transfer of electrons in the photosynthetic redox chain is achieved by the formation of short-lived complexes of cytochrome b6f with the electron transfer proteins plastocyanin and cytochrome c6. A balance must ...
Preface to the mini-theme issue of IUBMB life on biointeractomics [Article]
(Taylor & Francis, 2013)
Structural basis for inhibition of the histone chaperone activity of SET/TAF-Iβ by cytochrome c [Article]
(National Academy of Sciences, 2015)
Chromatin is pivotal for regulation of the DNA damage process insofar as it influences access to DNA and serves as a DNA repair docking site. Recent works identify histone chaperones as key regulators of damaged chromatin’s ...