dc.creator | Funuyet Salas, Jesús | es |
dc.creator | Martín Rodríguez, Agustín | es |
dc.creator | Pérez San Gregorio, María de los Ángeles | es |
dc.creator | Romero Gómez, Manuel | es |
dc.date.accessioned | 2021-05-24T08:11:32Z | |
dc.date.available | 2021-05-24T08:11:32Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Funuyet Salas, J., Martín Rodríguez, A., Pérez San Gregorio, M.d.l.Á. y Romero Gómez, M. (2021). Influence of Psychological Biomarkers on Therapeutic Adherence by Patients with Non-Alcoholic Fatty Liver Disease: A Moderated Mediation Model. Journal of Clinical Medicine, 10 (10), Article 2208. | |
dc.identifier.issn | 2077-0383 | es |
dc.identifier.uri | https://hdl.handle.net/11441/109241 | |
dc.description.abstract | Our aim was to analyze whether depressive symptoms mediated the association between
physical quality of life (QoL) and adherence to physical activity in patients with non-alcoholic fatty
liver disease (NAFLD), as well as the association between social support and adherence to diet.
We also examined whether self-efficacy exerted a moderating role in these associations. QoL (SF-12),
social support (MSPSS), depressive symptoms (HADS), self-efficacy (GSE), physical activity (IPAQ)
and diet (MEDAS) were evaluated in 413 biopsy-proven NAFLD patients. Mediation and moderated
mediation models were conducted using the SPSS PROCESS v3.5 macro. Results showed that
depressive symptoms mediated the relationship between physical QoL and adherence to physical
activity (indirect effect = 6.248, CI = 1.917–10.727), as well as the relationship between social support
and adherence to diet (indirect effect = 0.148, CI = 0.035–0.275). Self-efficacy also moderated the
indirect effects of QoL and social support on therapeutic adherence through depressive symptoms.
Specifically, the higher self-efficacy was, the lower the negative impact on the NAFLD patient’s
mental health. In conclusion, self-efficacy is defined as a protective factor for therapeutic adherence
by NAFLD patients with a psychosocial risk profile. Self-efficacy should, therefore, be a main
psychological target in future multidisciplinary NAFLD approaches. | es |
dc.description.sponsorship | FEDER/Ministerio de Ciencia e Innovación PSI2017-83365-P | es |
dc.description.sponsorship | Ministerio de Educación y Formación Profesional | es |
dc.description.sponsorship | Gilead Sciences | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Journal of Clinical Medicine, 10 (10), Article 2208. | |
dc.rights | Atribución 4.0 Internacional | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | NAFLD | es |
dc.subject | Therapeutic adherence | es |
dc.subject | Self-efficacy | es |
dc.subject | Quality of life | es |
dc.subject | Social support | es |
dc.subject | Depressive symptoms | es |
dc.subject | Physical activity | es |
dc.subject | Mediterranean diet | es |
dc.title | Influence of Psychological Biomarkers on Therapeutic Adherence by Patients with Non-Alcoholic Fatty Liver Disease: A Moderated Mediation Model | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Personalidad, Evaluación y Tratamiento Psicológicos | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.relation.projectID | PSI2017-83365-P | es |
dc.identifier.doi | 10.3390/jcm10102208 | es |
dc.journaltitle | Journal of Clinical Medicine | es |
dc.publication.volumen | 10 | es |
dc.publication.issue | 10 | es |
dc.publication.initialPage | Article 2208 | es |
dc.contributor.funder | Ministerio de Ciencia e Innovación (MICIN). España | es |
dc.contributor.funder | Ministerio de Educación y Formación Profesional. España | es |