Listar Química Orgánica por título
Mostrando ítems 238-257 de 464
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Artículo
Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery
(Elsevier, 2011-10)Fully homogeneous facial amphiphiles consisting in a cyclodextrin (CD) platform onto which a polycationic cluster and a ...
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Mantonico and Pecorello Grape Seed Extracts: Chemical Characterization and Evaluation of In Vitro Wound-Healing and Anti-Inflammatory Activities
(MDPI, 2020)The winemaking process produces a huge number of pomaces that generally are used for energy purposes. Further valuable ...
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Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7
(Nature Research (part of Springer Nature): Fully open access journals, 2019)P2X7 receptors are important in the regulation of inflammatory responses and immune responses to intracellular pathogens ...
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Masked Phenolic-Selenium Conjugates: Potent and Selective Antiproliferative Agents Overcoming P-gp Resistance
(MDPI, 2020)Cancer accounts for one of the most complex diseases nowadays due to its multifactorial nature. Despite the vast number ...
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Mechanically Planar-to-Point Chirality Transmission in [2]Rotaxanes
(American Chemical Society, 2024-01-24)Herein we describe an effective transmission of chirality, from mechanically planar chirality to point chirality, in ...
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Mechanistic Insight into the Binding of Multivalent Pyrrolidines to α-Mannosidases
(Wiley-Blackwell, 2017)Novel pyrrolidine-based multivalent iminosugars, synthesized by a CuAAC approach, have shown remarkable multivalent effects ...
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Metal- and metalloid-based compounds to target and reverse cancer multidrug resistance
(Elsevier, 2021)Drug resistance remains the major cause of cancer treatment failure especially at the late stage of the disease. However, ...
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Tesis Doctoral
Metodologías y estrategias de activación para la formilación catalítica enantioselectiva de compuestos carbonílicos
(2013-09-11)La adición de nucleófilos carbonados a dobles enlaces activados es una de las herramientas más poderosas en síntesis ...
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Molecular Determinants for Cyclo-oligosaccharide-based Nanoparticle-mediated Effective siRNA Transfection
(Future Medicine Ltd., 2017)Aim: To study the structural requirements that a cyclooligosaccharide-based nanoparticle must fulfill to be an efficient ...
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Molecular Recognition of Natural and Non-Natural Substrates by Cellodextrin Phosphorylase from Ruminiclostridium Thermocellum Investigated by NMR Spectroscopy
(Wiley-Blackwell, 2021)β-1→4-Glucan polysaccharides like cellulose, derivatives and analogues, are attracting attention due to their unique ...
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Monosaccharides and Analogues from Simple Achiral Unsaturated Compounds
(Schweizerische Chemische Gesellschaft, 2011)We present herein a selection of ingenious methods that have been developed to convert inexpensive furan, pyrrole and unsaturated hydrocarbons into enantiomerically enriched monosaccharides and analogues of biological interest.
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Multienzymatic processes involving baeyer–villiger monooxygenases
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Baeyer–Villiger monooxygenases (BVMOs) are flavin-dependent oxidative enzymes capable of catalyzing the insertion of an ...
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Multifrequency STD NMR Unveils the Interactions of Antibiotics With Burkholderia multivorans Biofilm Exopolysaccharide
(Frontiers Media S.A., 2021)Biofilms confine bacterial cells within self-produced matrices, offering advantages such as protection from antibiotics ...
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Multiply–linked cyclodextrin–aromatic hybrids: Caps, hinges and clips
(Taylor & Francis, 2019)The judicious combination of shaping and recognition elements in cage-type architectures represents a powerful strategy ...
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Multivalent glycoligands with lectin/enzyme dual specificity: self-deliverable glycosidase regulators
(Royal Society of Chemistry, 2019)Multivalent mannosides with inherent macrophage recognition abilities, built on β-cyclodextrin, RAFT cyclopeptide or peptide ...
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Multivalent glycosystems for human lectins
(Royal Society of Chemistry, 2022-08-30)Human lectins are involved in a wide variety of biological processes, both physiological and pathological, which have ...
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N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study
(Elsevier, 2020-05)Our goal was the evaluation of a series of N-1,2,3-triazole-isatin derivatives for multi-target activity which included ...
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N-Heterotricyclic Cationic Carbene Ligands. Synthesis, Reactivity and Coordination Chemistry
(Royal Society of Chemistry, 2018)The direct dialkylation of triazolo[4,3-b]isoquinolin-3-ylidene structures readily affords dicationic N-heterotricyclic ...
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N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer's Disease
(Elsevier, 2023-07-08)The oxindole core is an important structural motif in many natural and synthetic substances with various biological ...