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Listar Artículos (Microbiología) por autor "Pascual Hernández, Álvaro"
Mostrando ítems 81-100 de 107
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Prevalence and transmission dynamics of Escherichia coli ST131 among contacts of infected community and hospitalized patients
Torres, E.; López Cerero, Lorena; Navarro, M. D.; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro (Elsevier, 2018)Objectives: The Escherichia coli O25b-associated ST131 clonal group was recently found to be prevalent in our area as a ...
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Prevalence, Incidence, and Risk Factors for Intestinal Colonization Due to Fluoroquinolone-Resistant ST131 Escherichia coli: a Longitudinal Study in Highly Dependent, Long-Term Care Facility Residents
Salamanca Rivera, Elena; López Cerero, Lorena; Rodríguez Martínez, José Manuel; Pascual Hernández, Álvaro; Rodríguez-Baño, Jesús (American Society for Microbiology, 2022)Escherichia coli ST131 clade C is an important driver for fluoroquinolone resistance (FQ-R). We conducted a prospective ...
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Propensity score and desirability of outcome ranking analysis of ertapenem for treatment of nonsevere bacteremic urinary tract infections due to extended-spectrum-beta-lactamase-producing enterobacterales in kidney transplant recipients
Gutiérrez Gutiérrez, Belén; Pérez-Nadales, Elena; Pérez-Galera, Salvador; Cordero Matia, María Elisa; Pascual Hernández, Álvaro; Rodríguez-Baño, Jesús (American Society Microbiology, 2021)There are scarce data on the efficacy of ertapenem in the treatment of bacteremia due to extended-spectrum-beta-lactamase ...
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Prospective multicenter study of carbapenemase-producing Enterobacteriaceae from 83 hospitals in Spain reveals high in vitro susceptibility to colistin and meropenem
Conejo Gonzalo, Mª Carmen; Pascual Hernández, Álvaro; Otero, Jesús; Ortega, Adriana; Bartolomé, Rosa M.; Bou, Germán; Fernández Martínez, Marta; González López, Juan José (American Society for Microbiology, 2015-06-01)The aim of this study was to determine the impact of carbapenemase-producing Enterobacteriaceae (CPE) in Spain in 2013 by ...
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RecA inactivation as a strategy to reverse the heteroresistance phenomenon in clinical isolates of Escherichia coli
Díaz Díaz, S.; Yerbes, Pilar; Recacha, E.; De Gregorio Iaria, Belén; Pulido, Marina R.; Romero-Muñoz, María; Docobo Pérez, Fernando; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel (Elsevier, 2023-02)RecA inhibition could be an important strategy to combat antimicrobial resistance because of its key role in the SOS ...
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Reporting antimicrobial susceptibilities and resistance phenotypes in Staphylococcus spp.: a nationwide proficiency study
Fernández-Cuenca, Felipe; López Hernández, Inmaculada; Cercenado, Emilia; Conejo Gonzalo, Mª Carmen; Tormo, Nuria; Gimeno, Concha; Pascual Hernández, Álvaro (Oxford University Press, 2021-02-08)Objectives To evaluate the proficiency of microbiology laboratories in Spain in antimicrobial susceptibility testing (AST) ...
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Resistance of Pseudomonas aeruginosa to imipenem induced by eluates from siliconized latex urinary catheters is related to outer membrane protein alterations
Martínez Martínez, Luis; Pascual Hernández, Álvaro; Conejo Gonzalo, Mª Carmen; Picabea de la Peña, Leandro; Perea Pérez, Evelio José (American Society for Microbiology, 1999-02-01)The activity of imipenem against Pseudomonas aeruginosa HUS-3 decreased by 16 times in the presence of substances eluted ...
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Risk Factors and Prognosis of Nosocomial Bloodstream Infections Caused by Extended-Spectrum-B-Lactamase-Producing Escherichia coli
Rodríguez-Baño, Jesús; Picón, Encarnación; Gijón, Paloma; Hernández, José Ramón; Cisneros, José Miguel; Peña, Carmen; Almela, Manuel; Almirante, Benito; Grill, Fabio; Colomina, Javier; Molinos, Sonia; Oliver, Antonio; Fernández-Mazarrasa, Carlos; Navarro, Gemma; Coloma, Ana; López Cerero, Lorena; Pascual Hernández, Álvaro (American Society for Microbiology, 2010-05)Extended-spectrum-B-lactamase (ESBL)-producing Escherichia coli (ESBLEC) is an increasing cause of community and nosocomial ...
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Role of Klebsiella pneumoniae LamB porin in antimicrobial resistance
Doménech Sánchez, Antonio; Martínez Martínez, Luis; Hernández Allés, Santiago; Conejo Gonzalo, Mª Carmen; Pascual Hernández, Álvaro; Tomás, Juan M.; Albertí, Sebastián; Benedí, Vicente J. (American Society for Microbiology, 2003-10-01)To investigate the contribution of LamB in Klebsiella pneumoniae antimicrobial resistance, we determined the MICs of various ...
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Role of low-level quinolone resistance in generating tolerance in Escherichia coli under therapeutic concentrations of ciprofloxacin
Ortiz Padilla, Miriam; Díaz Díaz, S.; Machuca, J.; Tejada-Gonzalez, A.; Recacha, E.; Docobo Pérez, Fernando; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel (Oxford University Press, 2020)Background: Tolerance (including persistence) and resistance result in increased survival under antibiotic pressure. Objectives: ...
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Roles of β-Lactamases and Porins in Activities of Carbapenems and Cephalosporins against Klebsiella pneumoniae
Martínez Martínez, Luis; Pascual Hernández, Álvaro; Hernández Allés, Santiago; Álvarez Díaz, Dolores; Suárez, Ana Isabel; Tran, John; Benedí, Vicente J.; Jacoby, George A. (American Society for Microbiology, 1999-07-01)Two clinical isolates of extended-spectrum β-lactamase (ESBL)- producing Klebsiella pneumoniae were noted to be less ...
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Serum IFN-γ and RNAemia temporal profiles as biomarkers of severe COVID-19 in solid organ transplant and immunocompetent patients
Salto Alejandre, Sonsoles; Carretero-Ledesma, Marta; Camacho-Martínez, Pedro; Berastegui-Cabrera, Judith; Infante, Carmen; Rodríguez-Álvarez, Regino; Pérez Palacios, Patricia; Gómez Bravo, Miguel Ángel; Pascual Hernández, Álvaro; Lepe Jiménez, José Antonio; Rodríguez-Baño, Jesús; Cisneros, José Miguel; Pachón, Jerónimo; Sánchez-Céspedes, Javier; Cordero, Elisa; COVIDSOT working team (Elsevier, 2023) -
Artículo
Spanish Multicenter Study of the Epidemiology and Mechanisms of Amoxicillin-Clavulanate Resistance in Escherichia coli
Ortega, Adriana; Oteo, Jesús; Aranzamendi-Zaldumbide, Maitane; Bartolomé, Rosa M.; Bou, Germán; Cercenado, Emilia; Conejo Gonzalo, Mª Carmen; González-López, Juan José; Marín, Mercedes; Martínez-Martínez, Luis; Marino, María; Ferran, Navarro; Oliver, Antonio; Pascual Hernández, Álvaro; Rivera, Alba; Rodríguez-Baño, Jesús; Weber, Irene; Aracil, Belén; Campos, José (American Society for Microbiology, 2012-07)We conducted a prospective multicenter study in Spain to characterize the mechanisms of resistance to amoxicillin-clavu-lanate ...
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Synergistic effect of SOS response and GATC methylome suppression on antibiotic stress survival in Escherichia coli
Díaz Díaz, S.; Recacha, E.; Pulido, Marina R.; Romero Muñoz, María; De Gregorio Iaria, Belén; Docobo Pérez, Fernando; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel (https://journals.asm.org/doi/epdf/10.1128/aac.01392-22, 2023-03)The suppression of the SOS response has been shown to enhance the in vitro activity of quinolones. Furthermore, Dam-dependent ...
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Synergistic Quinolone Sensitization by Targeting the recA SOS Response Gene and Oxidative Stress
Recacha, E.; Machuca, J.; García Duque, A.; Docobo Pérez, Fernando; Blázquez, J.; Díaz Díaz, S.; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel (American Society for Microbiology, 2021-03-18)Suppression of the recA SOS response gene and reactive oxygen species (ROS) overproduction have been shown, separately, ...
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Temocillin versus meropenem for the targeted treatment of bacteraemia due to third-generation cephalosporin-resistant Enterobacterales (ASTARTÉ): protocol for a randomised, pragmatic trial
Marín Candón, Alicia; Rosso Fernández, Clara María; Bustos de Godoy, Natalia; López Cerero, Lorena; Gutiérrez Gutiérrez, Belén; López Cortés, Luis Eduardo; Merino Bohórquez, Vicente; Retamar Gentil, Pilar; Pascual Hernández, Álvaro; Rodríguez-Baño, Jesús (BMJ Publishing Group, 2021)Introduction: Alternatives to carbapenems are needed in the treatment of third-generation cephalosporin-resistant ...
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The role of PemIK (PemK/PemI) type II TA system from Klebsiella pneumoniae clinical strains in lytic phage infection
Bleriot, Inés; Blasco, Lucía; Palacios, Olga; Fernández García, Laura; Ambroa, Antón; López, María; Pascual Hernández, Álvaro; Tomás, María (Nature Publishing Group, 2022)Since their discovery, toxin-antitoxin (TA) systems have captivated the attention of many scientists. Recent studies have ...
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Uptake and intracellular activity of an optically active ofloxacin isomer in human neutrophils and tissue culture cells
Pascual Hernández, Álvaro; García Luque, Isabel; Perea Pérez, Evelio José (American Society for Microbiology, 1990-01-01)The penetration of an optically active ofloxacin isomer [(-)-ofloxacin] into human neutrophils and different tissue culture ...
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Uptake and intracellular activity of fluconazole in human polymorphonuclear leukocytes
Pascual Hernández, Álvaro; García Luque, Isabel; Conejo Gonzalo, Mª Carmen; Perea Pérez, Evelio José (American Society for Microbiology, 1993-01-01)The penetration of fluconazole into human polymorphonuclear leukocytes (PMNs) and tissue culture epithelial cells (McCoy) ...
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Uptake and intracellular activity of linezolid in human phagocytes and nonphagocytic cells
Pascual Hernández, Álvaro; Ballesta Mudarra, Sofía; García Luque, Isabel; Perea Pérez, Evelio José (American Society for Microbiology, 2002-12-01)The intracellular penetration and activity of linezolid in human polymorphonuclear leukocytes and tissue-cultured cells ...