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Listar Artículos (Microbiología) por autor "Pascual Hernández, Álvaro"
Mostrando ítems 41-60 de 107
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Artículo
Evaluation of temocillin efficacy against KPC-2-producing Klebsiella pneumoniae isolates in a hollow-fibre infection model
Rodríguez Ochoa, José Luis; Pérez Palacios, Patricia; Merino Bohórquez, Vicente; Ortiz Padilla, Miriam; Velázquez Escudero, Ana; Rodríguez-Baño, Jesús; Rodríguez Martínez, José Manuel; Pascual Hernández, Álvaro; Docobo Pérez, Fernando (Oxford University Press, 2024-02-09)Background: Temocillin is an old antimicrobial that is resistant to hydrolysis by ESBLs but has variable activity against ...
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Evaluation of three automated systems for susceptibility testing of enterobacteria containing qnrB, qnrS, and/or aac(6′)-Ib-cr
Calvo, Jorge; Cano, María Elicier; Pitart, Cristina; Marco, Francesc; Rodríguez Martínez, José Manuel; Pascual Hernández, Álvaro; Martínez Martínez, Luis (American Society for Microbiology, 2011)The accuracy of the MicroScan WalkAway, BD Phoenix, and Vitek-2 systems for susceptibility testing of quinolones and ...
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Excretion and viability of SARS‑CoV‑2 in feces and its association with the clinical outcome of COVID‑19
Cerrada Romero, Cristina; Berastegui-Cabrera, Judith; Camacho-Martínez, Pedro; Goikoetxea Aguirre, Josune; Pérez Palacios, Patricia; Santibáñez, Sonia; Pascual Hernández, Álvaro; Pachón Díaz, Jerónimo; Cordero Matia, María Elisa; Sánchez Céspedes, Javier (Nature Publishing Group, 2022)The main objective was to evaluate the viability of the SARS-CoV-2 viral particles excreted in stools. In addition, we ...
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Fatal levofloxacin failure in treatment of a bacteremic patient infected with Streptococcus pneumoniae with a preexisting parC mutation
Cueto López, Marina de; Rodríguez Martínez, José Manuel; Soriano Pérez, Manuel Jesús; López Cerero, Lorena; Venero Recio, José Luis; Pascual Hernández, Álvaro (American Society for Microbiology, 2008)The fatal outcome of levofloxacin treatment in a patient with bacteremic pneumonia caused by Streptococcus pneumoniae with ...
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Fosfomycin versus meropenem in bacteraemic urinary tract infections caused by extended-spectrum β-lactamase-producing Escherichia coli (FOREST): study protocol for an investigator-driven randomised controlled trial
Rosso Fernández, Clara; Sojo Dorado, Jesús; Barriga, Ángel; Lavín Alconero, Lucía; Palacios, Zaira; López Hernández, Inmaculada; Merino Bohórquez, Vicente; Cameán, Manuel; Pascual Hernández, Álvaro; Rodríguez-Baño, Jesús (BMJ Publishing Group, 2015)Introduction Finding therapeutic alternatives to carbapenems in infections caused by extended-spectrum β-lactamase-producing ...
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Four main virotypes among extended-spectrum-β-lactamase-producing isolates of Escherichia coli O25b:H4-B2-ST131: bacterial, epidemiological, and clinical characteristics
Blanco, Jorge; Mora, Azucena; Mamani, Rosalia; López, Cecilia; Blanco, Miguel; Dahbi, Ghizlane; Herrera, Alexandra; Marzoa, Juan; Fernández, Val; Cruz, Fernando de la; Martínez-Martínez, Luis; Alonso, María Pilar; Nicolas-Chanoine, Marie-Hélène; Johnson, James R.; Johnston, Brian; López Cerero, Lorena; Pascual Hernández, Álvaro; Rodríguez-Baño, Jesús (American Society for Microbiology, 2013-10)A total of 1,021 extended-spectrum- -lactamase-producing Escherichia coli (ESBLEC) isolates obtained in 2006 during a ...
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Genomewide overexpression screen for fosfomycin resistance in Escherichia coli: Mura confers clinical resistance at low fitness cost
Cauce, Alejandro; Briales, Alejandra; Rodríguez Rojas, Alexandro; Costas, Coloma; Pascual Hernández, Álvaro; Blázquez, Jesús (American Society for Microbiology, 2012-05-01)To determine whether the overexpression of chromosomal genes can confer fosfomycin resistance, genomewide screening of a ...
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Genomic analysis of 40 prophages located in the genomes of 16 carbapenemase-producing clinical strains of Klebsiella pneumoniae
Bleriot, Inés; Trastoy, Rocío; Blasco, Lucía; Fernández-Cuenca, Felipe; Ambroa, Antón; Fernández-García, Laura; Pascual Hernández, Álvaro; Tomás, María (2020)Klebsiella pneumoniae is the clinically most important species within the genus Klebsiella and, as a result of the continuous ...
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Global dissemination of a multidrug resistant Escherichia coli clone
Petty, Nicola K.; Ben Zakour, Nouri; Stanton-Cook, Mitchell; Skippington, Elizabeth; Totsika, Makrina; Forde, Brian M.; Phan, Minh-Duy; Gomes Moriel, Danilo; Peters, Kate M.; Davies, Mark; Rogers, Benjamin A.; Dougan, Gordon; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Pitout, Johann D. D.; Upton, Mathew; Paterson, David L.; Walsh, Timothy; Schembri, Mark; Beatson, Scott (National Academy of Sciences, 2014-04)Escherichia coli sequence type 131 (ST131) is a globally disseminated, multidrug resistant (MDR) clone responsible for a ...
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Artículo
Heterogeneity of SOS response expression in clinical isolates of Escherichia coli influences adaptation to antimicrobial stress
Díaz Díaz, Sara; García Montaner, Andrea; Vanni, Roberta; Murillo Torres, Marina; Recacha, Esther; Pulido, Marina R.; Romero Muñoz, María; Docobo Pérez, Fernando; Pascual Hernández, Álvaro; Rodríguez Martínez, José Manuel (Elsevier, 2024-04-23)In recent years, new evidence has shown that the SOS response plays an important role in the response to antimicrobials, ...
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Artículo
Household acquisition and transmission of extended-spectrum β-lactamase (ESBL) -producing Enterobacteriaceae after hospital discharge of ESBL-positive index patients
Riccio, Maria E.; Verschuuren, Tess; Conzelmann, Nadine; Martak, Daniel; Meunier, Alexandre; Salamanca, Elena; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Musicha, Patrick (Elsevier, 2021)Objectives: This study aimed to determine rates and risk factors of extended-spectrum b-lactamaseproducing Enterobacteriaceae ...
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Identification of a Stable Chromosomal Tandem Multicopy of bla(VIM-63), a New bla(VIM-2) Carbapenemase
Pulido, Marina R.; García Montaner, Andrea; López Cerero, Lorena; Fernández Cuenca, Felipe Manuel; Gutiérrez-Fernández, José; Pascual Hernández, Álvaro (American Society for Microbiology, 2022-07)This study characterizes a new genetic structure containing a multicopy of a bla(VIM-2) variant with an A676C substitution, ...
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Impact of De-escalation on Prognosis of Patients With Bacteremia due to Enterobacteriaceae: A Post Hoc Analysis From a Multicenter Prospective Cohort
Palacios-Baena, ZR; Delgado-Valverde, Mercedes; Mendez, AV; Almirante, Benito; Gomez-Zorrilla, S; Borrell, N; Corzo Delgado, Juan Enrique; Pascual Hernández, Álvaro; Rodríguez-Baño, Jesús; Cueto López, Marina de; Lepe Jiménez, José Antonio; Cisneros, José Miguel; Lara, R (Oxford University Press, 2019)Background More data are needed about the safety of antibiotic de-escalation in specific clinical situations as a ...
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Impact of the MIC of Piperacillin-Tazobactam on the Outcome of Patients with Bacteremia Due to Extended-Spectrum-B-Lactamase- Producing Escherichia coli
Retamar Gentil, Pilar; López Cerero, Lorena; Muniain Ezcurra, Miguel Angel; Pascual Hernández, Álvaro; Rodríguez-Baño, Jesús (American Society for Microbiology, 2013-07)We investigated the impact of the piperacillin-tazobactam MIC in the outcome of 39 bloodstream infections due to ...
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In vitro activities of ketolide HMR 3647, macrolides, and clindamycin against coryneform bacteria
Martínez Martínez, Luis; Pascual Hernández, Álvaro; Suárez, Ana Isabel; Perea Pérez, Evelio José (American Society for Microbiology, 1998-12-01)The in vitro activity of ketolide HMR 3647 against coryneform bacteria isolated from clinical samples was evaluated. Except ...
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In vitro activity of cefiderocol and comparators against isolates of Gram-negative bacterial pathogens from a range of infection sources: SIDERO‑WT‑2014−2018 studies in Spain
Cercenado, Emilia; Cardenoso, Laura; Penin, Rocio; Longshaw, Christopher; Henriksen, Anne Santerre; Pascual Hernández, Álvaro (Science Direct, 2021-07-15)Objectives: The incidence of antimicrobial resistance in Europe is rising. Cefiderocol is approved in Eu- rope for treatment ...
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Artículo
In Vitro Activity of Cefiderocol Compared to Other Antimicrobials against a Collection of Metallo-Beta-Lactamase-Producing Gram-Negative Bacilli from Southern Spain
Delgado Valverde, M.; Portillo Calderón, I.; Recacha, E.; Pérez Palacios, Patricia; Pascual Hernández, Álvaro (American Society for Microbiology, 2023)In this study, we aimed to comparatively evaluate the in vitro activity of cefiderocol versus other antimicrobials against ...
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Artículo
In vitro and in vivo efficacy of combinations of colistin and different endolysins against clinical strains of multi-drug resistant pathogens
Blasco, Lucia; Ambroa, Anton; Trastoy, Rocio; Bleriot, Ines; Moscoso, Miriam; Fernández-Garcia, Laura; Pascual Hernández, Álvaro; Tomas, Maria (Nature Research, 2020-04-28)The emergence of multidrug resistant (MDR) pathogenic bacteria is jeopardizing the value of antimicrobials, which had ...
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Artículo
In vitro effect of qnrA1, qnrB1, and qnrS1 genes on fluoroquinolone activity against isogenic Escherichia coli isolates with mutations in gyrA and parC
Briales, Alejandra; Rodríguez Martínez, José Manuel; González Velasco, Carmen; Díaz de Alba, Paula; Domínguez Herrera, Juan M.; Pachón Díaz, Jerónimo; Pascual Hernández, Álvaro (American Society for Microbiology, 2011-03-01)This article provides an analysis of the in vitro effect of qnrA1, qnrB1, and qnrS1 genes, combined with quinolone-resistant ...
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Artículo
Inoculum Effect on the Efficacies of Amoxicillin-Clavulanate, Piperacillin-Tazobactam, and Imipenem against Extended-Spectrum -Lactamase (ESBL)-Producing and Non-ESBL-Producing Escherichia coli in an Experimental Murine Sepsis Model
Docobo Pérez, Fernando; López Cerero, Lorena; López-Rojas, Rafael; Egea, P.; Domínguez-Herrera, J.; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Pachón Díaz, Jerónimo (American Society for Microbiology, 2013-04)Escherichia coli is commonly involved in infections with a heavy bacterial burden. Piperacillin-tazobactam and carbapenems ...