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Cellular Response to Ciprofloxacin in Low-Level Quinolone-Resistant Escherichia coli
(Frontiers Media, 2017)
Bactericidal activity of quinolones has been related to a combination of DNA fragmentation, reactive oxygen species (ROS) production and programmed cell death (PCD) systems. The underlying molecular systems responsible ...
PhD Thesis
PhD Thesis
PhD Thesis
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Resistencia a quinolonas mediada por plásmido en enterobacteriaceae
(2006)
En 1998, se describió por primera vez resistencia a quinolonas transmisible horizontalmente mediante un plásmido conjugativo. La diseminación horizontal de mecanismos de resistencia a fluoroquinolonas abre la posibilidad ...
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Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants
(BioMed Central, 2008)
Background Predicting antibiotic resistance before it emerges at clinical settings constitutes a novel approach for preventing and fighting resistance of bacterial pathogens. To analyse the possibility that novel ...
PhD Thesis
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Importancia de la desregulación de la degradación de proteínas del ciclo celular en el cáncer
(2019-06-14)
La viabilidad de las células depende del buen funcionamiento de un conjunto de mecanismos moleculares que controlan los procesos biológicos. La ubicuitilación de las proteínas permite degradar rápidamente los componentes ...
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Bovine tuberculosis in Doñana Biosphere Reserve: The role of wild ungulates as disease reservoirs in the last Iberian lynx strongholds
(Public Library of Science, 2008)
Doñana National Park (DNP) in southern Spain is a UNESCO Biosphere Reserve where commercial hunting and wildlife artificial feeding do not take place and traditional cattle husbandry still exists. Herein, we hypothesized ...
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Pol5 is an essential ribosome biogenesis factor required for 60S ribosomal subunit maturation in Saccharomyces cerevisiae
(Cold Spring Harbor Laboratory Press, 2019)
In Saccharomyces cerevisiae, more than 250 trans-acting factors are involved in the maturation of 40S and 60S ribosomal subunits. The expression of most of these factors is transcriptionally coregulated to ensure correct ...