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Artículo
The role of chromatin at transcription-replication conflicts as a genome safeguard
(Portland Press, 2021)
DNA replication ensures the correct copying of the genome and the faithful transfer of the genetic information to the offspring. However, obstacles to replication fork (RF) progression cause RF stalling and compromise ...
Artículo
The SWI/SNF complex, transcription-replication conflicts and cancer: a connection with high therapeutic potential
(Taylor & Francis, 2021)
Genome instability is a hallmark of cancer. ATP-dependent chromatin remodelers are frequently altered in cancer. We have recently reported that the SWItch/Sucrose Non-Fermentable (SWI/SNF) complex protects the genome by ...