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FACT Prevents the Accumulation of Free Histones Evicted from Transcribed Chromatin and a Subsequent Cell Cycle Delay in G1
(Public Library of Science, 2010)
The FACT complex participates in chromatin assembly and disassembly during transcription elongation. The yeast mutants affected in the SPT16 gene, which encodes one of the FACT subunits, alter the expression of G1 cyclins ...
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Identification of the Salmonella enterica damX gene product, an inner membrane protein involved in bile resistance
(American Society for Microbiology, 2010)
The damX gene product of Salmonella enterica serovar Typhimurium is a protein located in the inner membrane. DamX migrates as a 70-kDa protein in SDS-PAGE even though the predicted protein size is 46 kDa. Synthesis of DamX ...
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The THO complex as a key mRNP biogenesis factor in development and cell differentiation
(BioMed Central, 2010)
The THO complex is a key component in the co-transcriptional formation of messenger ribonucleoparticles that are competent to be exported from the nucleus, yet its precise function is unknown. A recent study in BMC Biology ...
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The salmonella type III secretion effector, Salmonella Leucine-rich Repeat Protein (SlrP), targets the human chaperone ERdj3
(Elsevier, 2010)
Effectors of the type III secretion systems (T3SS) are key elements in the interaction between many Gram-negative pathogens and their hosts. SlrP is an effector that is translocated into the eukaryotic host cell through ...
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Artículo
DNA resection in eukaryotes: deciding how to fix the break
(Natural Research, 2010)
DNA double-strand breaks are repaired by different mechanisms, including homologous recombination and nonhomologous end-joining. DNA-end resection, the first step in recombination, is a key step that contributes to the ...
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A glimpse into the basis of vision in the kingdom Mycota
(Elsevier, 2010)
Virtually all organisms exposed to light are capable of sensing this environmental signal. In recent years the photoreceptors that mediate the ability of fungi to " see" have been identified in diverse species, and ...