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Artículo
The Total mRNA Concentration Buffering System in Yeast is Global Rather than Gene-specific
(Cold Spring Harbor Laboratory Press, 2021)
Gene expression in eukaryotes does not follow a linear process from transcription to translation and mRNA degradation. Instead it follows a circular process in which cytoplasmic mRNA decay crosstalks with nuclear transcription. ...
Artículo
Enhanced Gene Regulation by Cooperation between mRNA Decay and Gene Transcription
(Elsevier, 2023)
It has become increasingly clear in the last few years that gene expression in eukaryotes is not a linear process from mRNA synthesis in the nucleus to translation and degradation in the cytoplasm, but works as a circular ...
Artículo
Nucleo-cytoplasmic Shuttling of RNA-binding Factors: mRNA Buffering and Beyond
(Elsevier, 2022)
Gene expression is a highly regulated process that adapts RNAs and proteins content to the cellular context. Under steady-state conditions, mRNA homeostasis is robustly maintained by tight controls that act on both nuclear ...