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Artículo
Prognostic value of CtIP/RBBP8 expression in breast cancer
(Wiley Open Access, 2013)
CtIP/RBBP8 is a multifunctional protein involved in transcription, DNA replication, DNA repair by homologous recombination and the G1 and G2 checkpoints. Its multiple roles are controlled by its interaction with several ...
Artículo
The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures
(Elsevier, 2018)
DNA breaks are complex lesions that can be repaired either by non-homologous end joining (NHEJ) or by homologous recombination (HR). The decision between these two routes of DNA repair is a key point of the DNA damage ...
Artículo
Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox
(Frontiers Media, 2020)
To ward off against the catastrophic consequences of persistent DNA double-strand breaks (DSBs), eukaryotic cells have developed a set of complex signaling networks that detect these DNA lesions, orchestrate cell cycle ...