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Mostrando ítems 61-70 de 461
Artículo
Single cell analysis of bistable expression of pathogenicity island 1 and the flagellar regulon in Salmonella enterica
(MDPI, 2021-01)
Bistable expression of the Salmonella enterica pathogenicity island 1 (SPI-1) and the flagellar network (Flag) has been described previously. In this study, simultaneous monitoring of OFF and ON states in SPI-1 and in the ...
Artículo
Role for RNA: DNA hybrids in origin-independent replication priming in a eukaryotic system
(National Academy of Sciences, 2015)
DNA replication initiates at defined replication origins along eukaryotic chromosomes, ensuring complete genome duplication within a single S-phase. A key feature of replication origins is their ability to control the onset ...
Artículo
Genome-Wide Identification and Expression Analysis of SOS Response Genes in Salmonella enterica Serovar Typhimurium
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
A bioinformatic search for LexA boxes, combined with transcriptomic detection of loci responsive to DNA damage, identified 48 members of the SOS regulon in the genome of Salmonella enterica serovar Typhimurium. Single cell ...
Artículo
Tubulin Folding Cofactor TBCB is a Target of the Salmonella Effector Protein SseK1
(MDPI, 2020)
Salmonella enterica serovar Typhimurium is a human and animal pathogen that uses type III secretion system effectors to manipulate the host cell and fulfill infection. SseK1 is a Salmonella effector with glycosyltransferase ...
Artículo
Identification and regulation of fusA, The polyketide synthase gene responsible for fusarin production in Fusarium fujikuroi
(American Society for Microbiology, 2012)
Fusarins are a class of mycotoxins of the polyketide family produced by different Fusarium species, including the gibberellin- producing fungus Fusarium fujikuroi. Based on sequence comparisons between polyketide synthase ...
Artículo
The CarO rhodopsin of the fungus Fusarium fujikuroi is a light-driven proton pump that retards spore germination
(Nature Publishing Group, 2015)
Rhodopsins are membrane-embedded photoreceptors found in all major taxonomic kingdoms using retinal as their chromophore. They play well-known functions in different biological systems, but their roles in fungi remain ...
Artículo
Analysis of al-2 mutations in neurospora
(Public Library of Science, 2011)
The orange pigmentation of the fungus Neurospora crassa is due to the accumulation of the xanthophyll neurosporaxanthin and precursor carotenoids. Two key reactions in the synthesis of these pigments, the formation of ...
Artículo
Nab2p and the Thp1p-Sac3p Complex Functionally Interact at the Interface between Transcription and mRNA Metabolism
(Elsevier, 2003)
THP1 is a conserved eukaryotic gene whose null mutations confer, in yeast, transcription and genetic instability phenotypes and RNA export defects similar to those of the THO/TREX complex null mutations. In a search for ...
Artículo
Chromatin reassembly factors are involved in transcriptional interference promoting HIV latency
(American Society for Microbiology, 2011)
The establishment of a stable reservoir of latently infected cells allows HIV to persist in the host. Usually, HIV infection of T cells results in integration of the viral genome, with a preference for regions in the human ...
Artículo
LeuO is a global regulator of gene expression in Salmonella enterica serovar Typhimurium
(Wiley-Blackwell, 2012)
We report the first investigation of the binding of the Salmonella enterica LeuO LysR-type transcription regulator to its genomic targets in vivo. Chromatin-immunoprecipitation-on-chip identified 178 LeuO binding sites on ...