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Mostrando ítems 221-230 de 452
Artículo
Deviations from temporal scaling support a stage-specific regulation for C. elegans postembryonic development
(BMC, 2022)
Background After embryonic development, Caenorhabditis elegans progress through for larval stages, each of them finishing with molting. The repetitive nature of C. elegans postembryonic development is considered an ...
Artículo
CRP-cAMP mediates silencing of Salmonella virulence at the post-transcriptional level
(Public Library of Science, 2018-06-07)
Invasion of epithelial cells by Salmonella enterica requires expression of genes located in the pathogenicity island I (SPI-1). The expression of SPI-1 genes is very tightly regulated and activated only under specific ...
Artículo
Biocontrol mechanisms of Thrichoderma strains
(Sociedad Española de MicrobiologÍa, 2004)
The genus Trichoderma comprises a great number of fungal strains that act as biological control agents, the antagonistic properties of which are based on the activation of multiple mechanisms. Trichoderma strains exert ...
Artículo
Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole-genome duplication
(Public Library of Science, 2009)
Rhizopus oryzae is the primary cause of mucormycosis, an emerging, life-threatening infection characterized by rapid angioinvasive growth with an overall mortality rate that exceeds 50%. As a representative of the paraphyletic ...
Artículo
Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants
(American Society for Microbiology, 2006)
THO is a protein complex that functions in cotranscriptional mRNP formation. Yeast THO1 and SUB2 (Saccharomyces cerevisiae) were identified as multicopy suppressors of the expression defects of the hpr1 mutant of THO. ...
Artículo
Analysis of Salmonella lineage-specific traits upon cell sorting
(Frontiers Media SA, 2023-03-29)
Microbial cell individuality is receiving increasing interest in the scientific community. Individual cells within clonal populations exhibit noticeable phenotypic heterogeneity. The advent of fluorescent protein technology ...
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Artículo
The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two β-propellers during the assembly of large ribosomal subunits in eukaryotes
(Oxford University Press, 2015)
Ribosome biogenesis is one of the most essential pathways in eukaryotes although it is still not fully characterized. Given the importance of this process in proliferating cells, it is obvious that understanding the ...
Artículo
Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability
(National Academy of Sciences, 2017)
During transcription, the mRNA may hybridize with DNA, forming an R loop, which can be physiological or pathological, constituting in this case a source of genomic instability. To understand the mechanism by which eukaryotic ...
Artículo
Nucleosome-mediated synergism between transcription factors on the mouse mammary tumor virus promoter
(National Academy of Sciences, 1997)
In unstimulated mammalian cells and in Saccharomyces cerevisiae, the mouse mammary tumor virus (MMTV) promoter is silent and organized into positioned nucleosomes, one of which encompasses the binding sites for glucocorticoid ...