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Mostrando ítems 191-200 de 452
Artículo
Balanced production of ribosome components is required for proper G/S transition in saccharomyces cerevisiae
(American Society for Biochemistry and Molecular Biology Inc., 2013)
Artículo
Defective nucleotide excision repair in yeast hpr1 and tho2 mutants
(Oxford University Press, 2002)
Nucleotide excision repair (NER) and transcription are intimately related. First, TFIIH has a dual role in transcription initiation and NER and, secondly, transcription leads to more efficient repair of damage present in ...
Artículo
Fungal stress biology: a preface to the Fungal Stress Responses special edition
(Springer Nature, 2015)
There is currently an urgent need to increase global food security, reverse the trends of increasing cancer rates, protect environmental health, and mitigate climate change. Toward these ends, it is imperative to improve ...
Artículo
The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons
(Oxford University Press, 2016)
We analyzed 80 different genomic experiments, and found a positive correlation between both RNA polymerase II transcription and mRNA degradation with growth rates in yeast. Thus, in spite of the marked variation in mRNA ...
Artículo
TFIIS is required for the balanced expression of the genes encoding ribosomal components under transcriptional stress
(Oxford University Press, 2012)
Transcription factor IIS (TFIIS) stimulates RNA cleavage by RNA polymerase II by allowing backtracked enzymes to resume transcription elongation. Yeast cells do not require TFIIS for viability, unless they suffer severe ...
Artículo
Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery
(Rockefeller University Press, 2009)
The evolutionarily conserved protein Sem1/Dss1 is a subunit of the regulatory particle (RP) of the proteasome, and, in mammalian cells, binds the tumor suppressor protein BRCA2. Here, we describe a new function for yeast ...
Artículo
Draft genome sequence of methanobacterium formicicum DSM 3637, an archaebacterium isolated from the methane producer amoeba pelomyxa palustris
(American Society for Microbiology, 2012)
Here is reported the draft genome sequence of Methanobacterium formicicum DSM 3637, which was isolated from the methane- producing amoeba Pelomyxa palustris. This bacterium was determined to be an endosymbiont living in ...
Artículo
Metabolite repression and inducer exclusion in the proline utilization gene cluster of Aspergillus nidulans
(American Society for Microbiology, 2000)
The clustered prnB, prnC, and prnD genes are repressed by the simultaneous presence of glucose and ammonium. A derepressed mutation inactivating a CreA-binding site acts in cis only on the permease gene (prnB) while ...
Artículo
The eukaryote-specific N-terminal extension of ribosomal protein S31 contributes to the assembly and function of 40S ribosomal subunits
(Oxford University Press, 2016)
The archaea-/eukaryote-specific 40S-ribosomal-subunit protein S31 is expressed as an ubiquitin fusion protein in eukaryotes and consists of a conserved body and a eukaryote-specific N-terminal extension. In yeast, S31 is ...
Artículo
DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
(Elsevier, 2023)
Unscheduled R loops can be a source of genome instability, a hallmark of cancer cells. Although targeted proteomic approaches and cellular analysis of specific mutants have uncovered factors potentially involved in R-loop ...