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Mostrando ítems 131-140 de 452
Artículo
Special Issue: Type III Secretion Systems in Human/Animal Pathogenic Bacteria
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Artículo
Nuclear ingression of cytoplasmic bodies accompanies a boost in autophagy
(Rockefeller University Press, 2022)
Membrane contact sites are functional nodes at which organelles reorganize metabolic pathways and adapt to changing cues. In Saccharomyces cerevisiae, the nuclear envelope subdomain surrounding the nucleolus, very plastic ...
Artículo
The THO complex as a key mRNP biogenesis factor in development and cell differentiation
(BioMed Central, 2010)
The THO complex is a key component in the co-transcriptional formation of messenger ribonucleoparticles that are competent to be exported from the nucleus, yet its precise function is unknown. A recent study in BMC Biology ...
Artículo
An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination
(American Society for Microbiology, 2006)
THO/TREX, a conserved eukaryotic protein complex, is a key player at the interface between transcription and mRNP metabolism. The lack of a functional THO complex impairs transcription, leads to transcriptiondependent ...
Artículo
Development of a new fluorescent reporter:operator system: location of AraC regulated genes in Escherichia coli K-12
(BioMed Central, 2017)
In bacteria, many transcription activator and repressor proteins regulate multiple transcription units that are often distally distributed on the bacterial genome. To investigate the subcellular location of DNA bound ...
Artículo
Expansion of Signal Transduction Pathways in Fungi by Extensive Genome Duplication
(Elsevier, 2016)
Plants and fungi use light and other signals to regulate development, growth, and metabolism. The fruiting bodies of the fungus Phycomyces blakesleeanus are single cells that react to environmental cues, including light, ...
Artículo
Guidelines and recommendations on yeast cell death nomenclature
(Shared Science Publishers, 2018)
Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of the most critical processes determining yeast life and physiology is cellular demise. However, the ...
Artículo
Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans
(Springer Nature, 2018)
Background: Advances in automated image-based microscopy platforms coupled with high-throughput liquid workflows have facilitated the design of large-scale screens utilising multicellular model organisms such as Caenorhabditis ...
Artículo
Role of the RecBCD recombination pathway in Salmonella virulence
(American Society for Microbiology, 2002)
Mutants of Salmonella enterica lacking the RecBC function are avirulent in mice and unable to grow inside macrophages (N. A. Buchmeier, C. J. Lipps, M. Y. H. So, and F. Heffron, Mol. Microbiol. 7:933-936, 1993). The ...
Artículo
Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability
(2018)
R loops are nucleic acid structures comprising an DNA-RNA hybrid and a displaced single-stranded DNA. These structures may occur transiently during transcription, playing essential biological functions. However, persistent ...