ListarArtículos (Genética) por materia "R loops"
Mostrando ítems 1-5 de 5
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Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability
(2018)R loops are nucleic acid structures comprising an DNA-RNA hybrid and a displaced single-stranded DNA. These structures may ...
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The Npl3 hnRNP prevents R-loop-mediated transcription–replication conflicts and genome instability
(Cold Spring Harbor Laboratory Press, 2013)Transcription is a major obstacle for replication fork (RF) progression and a cause of genome instability. Part of this ...
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The yeast and human FACT chromatin-reorganizing complexes resolve R-loop-mediated transcription-replication conflicts
(Cold Spring Harbor Laboratory Press, 2014)FACT (facilitates chromatin transcription) is a chromatin-reorganizing complex that swaps nucleosomes around the RNA ...
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Topoisomerase 1-dependent R-loop deficiency drives accelerated replication and genomic instability
(Elsevier, 2022)DNA replication is a complex process tightly regulated to ensure faithful genome duplication, and its perturbation leads ...
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UAP56/DDX39B is a major cotranscriptional RNA–DNA helicase that unwinds harmful R loops genome-wide
(Cold Spring Harbor Laboratory Press, 2020)Nonscheduled R loops represent a major source of DNA damage and replication stress. Cells have different ways to prevent ...