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PhD Thesis
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Función de la sumoilación en el desarrollo del sistema nervioso central de vertebrados
(2017-07-11)
La formacion del Sistema Nervioso Central (SNC) y la diferenciacion de neuronas, celulas gliales y otros tipos celulares que lo conforman, son procesos esenciales que implican un gran número de eventos celulares que tienen ...
Article
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An ER-Localized SNARE Protein Is Exported in Specific COPII Vesicles for Autophagosome Biogenesis
(Elsevier (Cell Press): OAJ, 2016)
The de novo formation of autophagosomes for the targeting of cytosolic material to the vacuole/lysosome is upregulated upon starvation. How autophagosomes acquire membranes remains still unclear. Here, we report that, in ...
Article
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CtIP Mutations Cause Seckel and Jawad Syndromes
(Public Library of Science, 2011)
Seckel syndrome is a recessively inherited dwarfism disorder characterized by microcephaly and a unique head profile. Genetically, it constitutes a heterogeneous condition, with several loci mapped (SCKL1-5) but only three ...
PhD Thesis
PhD Thesis
PhD Thesis
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Bases genéticas de las respuestas a la luz de "Phycomyces blakesleeanus"
(1979)
En este trabajo se han estudiado las bases genéticas de varias respuestas de Phycomyces a la luz, concluyéndose que:1. El contenido de ß-caroteno de estirp ... e silvestre, aumenta en función de los valores absolutos de ...
Article
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Chromosomal translocations caused by either Pol32-dependent or Pol32-independent triparental break-induced replication
(American Society for Microbiology, 2009)
Double-strand breaks (DSBs) are harmful DNA lesions that can generate chromosomal rearrangements or chromosome losses if not properly repaired. Despite their association with a number of genetic diseases and cancer, the ...
Article
Article
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Variation in G+C-content and codon choice: Differences among synonymous codon groups in vertebrate genes
(Oxford University Press, 1989)
The relationship between G+C-content and codon usage in genes of human, mus, rat, bovine and chicken nuclear genomes was investigated. Correlation and lineal regression analyses were carried out on plots that related the ...
Article
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Regulation of transcription elongation in response to osmostress
(Public Library of Science, 2017)
Cells trigger massive changes in gene expression upon environmental fluctuations. The Hog1 stress-activated protein kinase (SAPK) is an important regulator of the transcriptional activation program that maximizes cell ...