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Impaired manganese metabolism causes mitotic misregulation
(American Society for Biochemistry and Molecular Biology, 2012)
Manganese is an essential trace element, whose intracellular levels need to be carefully regulated. Mn2+ acts as a cofactor for many enzymes and excess of Mn2+ is toxic. Alterations in Mn2+ homeostasis affect metabolic ...
Tesis Doctoral
Artículo
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Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex
(American Society for Microbiology, 2006)
THO/TREX is a conserved, eukaryotic protein complex operating at the interface between transcription and messenger ribonucleoprotein (mRNP) metabolism. THO mutations impair transcription and lead to increased transcrip ...
Artículo
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Identification of the Salmonella enterica damX gene product, an inner membrane protein involved in bile resistance
(American Society for Microbiology, 2010)
The damX gene product of Salmonella enterica serovar Typhimurium is a protein located in the inner membrane. DamX migrates as a 70-kDa protein in SDS-PAGE even though the predicted protein size is 46 kDa. Synthesis of DamX ...
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Unexpected homology between inducible cell wall protein QID74 of filamentous fungi and BR3 salivary protein of the insect Chironomus
(National Academy of Sciences, 1998)
A gene, qid74, of mycoparasitic filamentous fungus Trichoderma harzianum and its allies encodes a cell wall protein that is induced by replacing glucose in the culture medium with chitin (simulated mycoparasitism conditions). ...
Tesis Doctoral
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Evolución y caracterización de las poblaciones de levaduras responsables de la crianza biológica del vino de Jérez
(1995)
La crianza biológica del vino de la zona de Jerez constituye una etapa fundamental en su singular elaboración. La evolución que registra el vino durante esta fase es muy marcada, llevando implícitas modificaciones muy ...
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Artículo
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The Fanconi Anemia Pathway Protects Genome Integrity from R-loops
(Public Library of Science, 2015)
Co-transcriptional RNA-DNA hybrids (R loops) cause genome instability. To prevent harmful R loop accumulation, cells have evolved specific eukaryotic factors, one being the BRCA2 double-strand break repair protein. As BRCA2 ...
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Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration
(Taylor & Francis, 2021)
mRNA homoeostasis is favoured by crosstalk between transcription and degradation machineries. Both the Ccr4-Not and the Xrn1-decaysome complexes have been described to influence transcription. While Ccr4-Not has been shown ...
Tesis Doctoral
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Mejora genética de levaduras implicadas en la elaboración de vinos tipo Fino
(2011)
Los objetivos de este trabajo han sido: 1. La mejora de las propiedades organolépticas en los vinos sometidos a crianza biológica mediante la obtención de cepas fermentativas superproductoras de L-fenilalanina y/o que ...