Browsing Artículos (Biología Celular) by Subject "Homologous recombination"
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Article
BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis
(Nature Research, 2024-05-20)Deficiencies in the BRCA1 tumor suppressor gene are the main cause of hereditary breast and ovarian cancer. BRCA1 is ...
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Article
Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination
(Elsevier, 2017)Zebularine is a second-generation, highly stable hydrophilic inhibitor of DNA methylation with oral bioavailability that ...