- idUS
- Investigación
- Ciencias
- Biología Celular
- Artículos (Biología Celular)
- Listar Artículos (Biología Celular) por autor
Listar Artículos (Biología Celular) por autor "López Lázaro, Miguel"
Mostrando ítems 1-9 de 9
-
Artículo
5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair
Orta Vázquez, Manuel Luis; Calderón Montaño, José Manuel; Domínguez García, Inmaculada; Pastor Carrillo, Nuria María; Burgos Morón, Estefanía; López Lázaro, Miguel; Cortés, Felipe; Mateos Cordero, Santiago; Helleday, Thomas (Oxford University Press, 2013)5-Aza-2'-deoxycytidine (5-azadC) is a DNA methyltransferase (DNMT) inhibitor increasingly used in treatments of hematological ...
-
Artículo
A hydroalcoholic extract from the leaves of Nerium oleander inhibits glycolysis and induces selective killing of lung cancer cells
Calderón Montaño, José Manuel; Burgos Morón, Estefanía; Orta Vázquez, Manuel Luis; Mateos Cordero, Santiago; López Lázaro, Miguel (Georg Thieme Verlag, 2013)Recent evidence suggests that cardiac glycosides might be used for the treatment of cancer. The ornamental shrub Nerium ...
-
Artículo
Anti-tumour activity of Digitalis purpurea L. subsp. heywoodii
López Lázaro, Miguel; Palma de la Peña, Nieves; Pastor Carrillo, Nuria María; Martín Cordero, Carmen; Navarro, Eduardo; Cortés Benavides, Felipe; Ayuso, María Jesús; Toro Sainz, María Victoria (Georg Thieme Verlag, 2003)Recent research has shown the anticancer effects of digitalis compounds suggesting their possible use in medical oncology. ...
-
Artículo
Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
Burgos Morón, Estefanía; Calderón Montaño, José Manuel; Orta Vázquez, Manuel Luis; Guillén Mancina, Emilio; Mateos Cordero, Santiago; López Lázaro, Miguel (MDPI AG, 2016)Epidemiological studies have found a positive association between coffee consumption and a lower risk of cardiovascular ...
-
Artículo
Effect of DNA repair deficiencies on the cytotoxicity of resveratrol
López Lázaro, Miguel; Burgos Morón, Estefanía; Calderón Montaño, José Manuel; Orta Vázquez, Manuel Luis; Mateos Cordero, Santiago (2015)Numerous preclinical studies have shown that the naturally-occurring polyphenol resveratrol may produce health-beneficial ...
-
Artículo
Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside
Burgos Morón, Estefanía; Pastor Carrillo, Nuria María; Orta Vázquez, Manuel Luis; Jiménez Alonso, Julio José; Vega Holm, Margarita; Vega Pérez, José Manuel; Iglesias Guerra, Fernando; Mateos Cordero, Santiago; López Lázaro, Miguel; Calderón Montaño, José Manuel (Wiley, 2018)Several clinically useful anticancer drugs selectively kill cancer cells by inducing DNA damage; the genomic instability ...
-
Artículo
The Cockayne syndrome protein B is involved in the repair of 5-AZA-2′-deoxycytidine-induced DNA lesions
Burgos Morón, Estefanía; Calderón Montaño, José Manuel; Pastor Carrillo, Nuria María; Ruiz Castizo, Ángel; Domínguez García, Inmaculada; López Lázaro, Miguel; Mateos Cordero, Santiago; Orta Vázquez, Manuel Luis (Impact Journals, 2018)The Cockayne Syndrome Protein B (CSB) plays an essential role in Transcription-Coupled Nucleotide Excision Repair (TC-NER) ...
-
Artículo
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions
Orta Vázquez, Manuel Luis; Calderón Montaño, José Manuel; Domínguez García, Inmaculada; Burgos Morón, Estefanía; Pastor Carrillo, Nuria María; López Lázaro, Miguel; Helleday, Thomas (Oxford University Press, 2014)Decitabine (5-aza-21-deoxycytidine, 5-azadC) is used in the treatment of Myelodysplatic syndrome (MDS) and Acute Myeloid ...
-
Artículo
Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination
Orta Vázquez, Manuel Luis; Pastor Carrillo, Nuria María; Burgos Morón, Estefanía; Domínguez García, Inmaculada; Calderón Montaño, José Manuel; Huertas Castaño, Carlos; López Lázaro, Miguel; Helleday, Thomas; Mateos Cordero, Santiago (Elsevier, 2017)Zebularine is a second-generation, highly stable hydrophilic inhibitor of DNA methylation with oral bioavailability that ...